林产化学与工业2024，Vol.44Issue(4)：121-129,9.DOI:10.3969/j.issn.0253-2417.2024.04.015
木质素基多酚的制备及生物活性
Preparation and Bioactivities of Lignin-based Polyphenols
摘要
Abstract
Aiming at the problems of low active sites and poor activity of lignin,pyrogallol modified enzymatic hydrolyzed lignin(PEHL),a lignin-based polyphenol compound,was prepared by one-pot demethylation and phenolic modification from acidic molten salt hydrate.The experimental results demonstrated a significant increase in the reaction sites of demethylated enzymatic hydrolyzed lignin(DEHL)and PEHL,with phenolic hydroxyl groups increasing from 1.25 mmol/g in raw enzymatic hydrolyzed lignin(EHL)to 3.49 and 5.70 mmol/g,respectively.Furthermore,DPPH·scavenging experiments revealed a significant enhancement in the antioxidant activities of lignin-based polyphenol compounds,and the DPPH·scavenging rates of DEHL and PEHL increased by 46.9％and 64.4％,respectively.Moreover,PEHL showed promising antibacterial activity,and low cytotoxicity with inhibition rates of E.coli and S.aureus by 85.22％and 99.76％,respectively.关键词
木质素/结构改性/脱甲基化木质素/酚化改性/生物活性Key words
lignin/structure modification/demethylated lignin/phenolic modification/bioactivity evaluation分类
化学化工引用本文复制引用
李龙,卫海琳,王雯蕾,张评浒,周永红,杨晓慧..木质素基多酚的制备及生物活性[J].林产化学与工业,2024,44(4):121-129,9.基金项目
国家自然科学基金资助项目(32071718) （32071718）
江苏省生物质能源与材料重点实验室资助项目(JSBEM-S-201803) （JSBEM-S-201803）
