糖尿病酮症酸中毒临床误诊分析OACSTPCD
Analysis of Clinical Misdiagnosis of Diabetic Ketoacidosis
目的 分析糖尿病酮症酸中毒(DKA)的误诊原因,提高临床医生对该病的警惕性和诊断准确率.方法 回顾分析2020 年至2023 年收治的3 例初诊为其他疾病的DKA患者的临床资料.结果 1 例初始表现为上腹部剧烈疼痛、恶心及呕吐等,经实验室检查考虑为急性胰腺炎;1 例主要症状为腹胀、腹痛和便秘,初诊为肠梗阻;1 例主要表现为突发性头痛和意识障碍,初诊为急性脑血管意外.3 例均经相关治疗后病情未见明显改善,并进一步行血糖、尿酮体及动脉血气分析,血糖显著升高,尿酮体强阳性,动脉血气分析显示代谢性酸中毒,均确诊为DKA.误诊时间1~4d.3 例确诊后均接受胰岛素和补液等治疗,病情明显改善,预后良好.结论 DKA临床表现多样,且缺乏特异性,容易与其他急症混淆,需早期行血糖、尿酮体和动脉血气分析等检查,以便及时识别和诊断DKA,避免误诊导致的不良后果.
Objective To analyze the causes of misdiagnosis of diabetic ketoacidosis(DKA),so as to improve the vigilance and diagnostic accuracy of clinicians.Methods The clinical data of 3 DKA patients initially diagnosed with other diseases from 2020 to 2023 were retrospectively analyzed.Results One patient initially presented with severe upper abdomi-nal pain,nausea and vomiting,and was considered to have acute pancreatitis by laboratory examination.The main symptoms of 1 patient were abdominal distension,abdominal pain and constipation,with initial diagnosis of intestinal obstruction.One patient presented with sudden headache and disturbance of consciousness and was initially diagnosed with acute cerebrovascu-lar accident.After relevant treatment,the condition of the 3 patients did not improve significantly.Further examinations,in-cluding blood glucose,urinary ketone body and arterial blood gas analysis,showed significant increase in blood glucose,strong positive urinary ketone body,and arterial blood gas analysis showed metabolic acidosis;all were diagnosed with DKA.The duration of misdiagnosis was 1-4 d.After diagnosis,all the 3 patients received insulin and rehydration therapy,and their conditions were significantly improved with a good prognosis.Conclusion The clinical manifestations of DKA are diverse and lack specificity,which is more likely to be confused with other emergencies.Early blood glucose,urinary ketone body and ar-terial blood gas analysis should be performed as early as possible in order to timely identify and diagnose DKA and avoid ad-verse consequences caused by misdiagnosis.
陶雅辉;房胜辉;李文会
063000 河北 唐山,唐山市第二医院综合内科
临床医学
糖尿病酮症酸中毒误诊胰腺炎肠梗阻脑血管意外血糖尿酮体动脉血气分析
Diabetes mellitusKetoacidosisMisdiagnosisPancreatitisIntestinal obstructionCerebrovascular ac-cidentBlood SugarUrinary ketone bodiesArterial blood gas analysis
《临床误诊误治》 2024 (014)
10-13 / 4
河北省2016年度医学科学研究重点课题计划项目(20160904)
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