皮肤性病诊疗学杂志2024，Vol.31Issue(8)：518-523,6.DOI:10.3969/j.issn.1674-8468.2024.08.002
炎症性肠病伴皮肤表现的临床与病理分析
Clinical and pathological analyses of two cases of inflammatory bowel disease with cutane-ous manifestations
摘要
Abstract
Objective To analyze the clinical and histopathological features of skin manifesta-tions of inflammatory bowel disease(IBD)in order to provide guidance for clinical diagnosis.Meth-ods Clinical and pathological characteristics of 2 patients with IBD were retrospectively analyzed.Results One patient had Crohn's disease manifested by perianal erythema and ulcers,and histopa-thology showed non-caseous and non-infectious granuloma in the dermis.Treatment with Ustekinum-ab decreased the ulcerative area.In another case of ulcerative colitis with extraintestinal manifesta-tions,erythemas and nodules were all over the body,and ulcers were on the lower legs and but-tocks.Histopathology showed dermal neutrophil infiltration.The skin lesions partially subsided after the treatment with Infliximab.Conclusions IBD with cutaneous manifestations has different his-topathological characteristics,and clinicians should make the diagnosis based on both clinical mani-festations and histopathological features in order to avoid misdiagnosis and missed diagnosis.关键词
炎症性肠病/克罗恩病/溃疡性结肠炎/皮肤表现/病理特点Key words
inflammatory bowel disease/Crohn's disease/ulcerative colitis/skin mani-festations/pathological features引用本文复制引用
丘晓英,夏传刚,肖文,陈方如..炎症性肠病伴皮肤表现的临床与病理分析[J].皮肤性病诊疗学杂志,2024,31(8):518-523,6.基金项目
桂林市卫生健康委医美康养人才小高地建设项目 （）
柳州市科技计划项目(2022CAC0227) （2022CAC0227）
广西壮族自治区卫生和计划生育委员会自筹经费科研课题(Z20170846) （Z20170846）
