皮肤性病诊疗学杂志2024，Vol.31Issue(8)：542-545,4.DOI:10.3969/j.issn.1674-8468.2024.08.006
乌帕替尼治疗重度斑秃12例短期疗效观察
Short term efficacy of Upatinib in the treatment of 12 patients with severe alopecia areata
尚智伟 1汪文翠 1夏丽晔1
作者信息
- 1. 河南科技大学临床医学院河南科技大学第一附属医院,河南 洛阳 471003
- 折叠
摘要
Abstract
Objective To observe short term efficacy and safety of Upatinib in the treatment of severe alopecia areata.Methods From March 2023 to March 2024,12 patients with severe alo-pecia areata were treated orally with sustained-release tablets of Upatinib at the dermatology outpa-tient clinic of the First Affiliated Hospital of Henan University of Science and Technology.After 12 weeks of the treatment,the clinical efficacy and adverse reactions were evaluated.Results After 12 weeks of the treatment,there were 10 patients(83.33％)with SALT≤20 points.The average hair density was increased from 29.42±3.23/0.46 cm2 at baseline to 35.50±2.87/0.46 cm2(t=27.62,P＜0.001).The average hair diameter was also increased from(39.58±2.35)µm to(67.75±6.43)μm(t=14.26,P＜0.001).No serious adverse reactions were observed in all patients.Conclusions Upatinib is effective and safe for severe alopecia areata,and can be an optional therapeutic approach for severe alopecia areata.关键词
乌帕替尼/斑秃/重度/疗效观察Key words
Upatinib/alopecia areata/severe/observation on the efficacy引用本文复制引用
尚智伟,汪文翠,夏丽晔..乌帕替尼治疗重度斑秃12例短期疗效观察[J].皮肤性病诊疗学杂志,2024,31(8):542-545,4.
