皮肤性病诊疗学杂志2024，Vol.31Issue(8)：546-550,5.DOI:10.3969/j.issn.1674-8468.2024.08.007
Stevens-Johnson综合征和中毒性表皮坏死松解症患者护理的回顾性分析
A retrospective analysis of nursing patients with Stevens-Johnson syndrome or toxic epider-mal necrolysis
摘要
Abstract
Objective To summarize and analyze the skin care methods for and outcomes of pa-tients with Stevens-Johnson syndrome(SJS)or toxic epidermal necrolysis(TEN).Methods Inpa-tients with SJS or TEN at Dermatology Hospital of Southern Medical University from January 2016 to February 2023 were retrospectively analyzed.The changes in the total body surface area(BSA),control time,healing time,hospitalization days and complications of skin lesions during hospitaliza-tion were analyzed.Results Forty-one patients were included.Fourteen patients were treated with dry powder exfoliation,while 16 patients were treated with wet-dress healing care.The rest 11 cases were treated with the combination of dry powder exfoliation,moist bum ointment and vaseline gauze.On the 5th day,treatment with either dry powder exfoliation or wet-dress healing care signifi-cantly decreased the BSA(t=5.25,6.28,P＜0.001).On the 9th day,the combination care also markedly decreased BSA from the baseline(t=2.03,P=0.042).There was no significant differ-ence in the incidence of complications among the three nursing models(P=0.827).Conclusions In combination with systemic treatments,early dry powder exfoliation and later wet dressing care can quickly improve skin lesions and shorten hospitalization time.Clinically,different nursing models should be adopted according to the manifestations of skin lesions in different phases.关键词
Stevens-Johnson综合征/中毒性表皮坏死松解症/护理/粉床/银离子敷料Key words
Stevens-Johnson syndrome/toxic epidermal necrolysis/nursing/powder bed/silver dressings引用本文复制引用
何雪瑜,刘嘉琪,陈荣,曾小芳,王宇,陈慕刁,刘红芳..Stevens-Johnson综合征和中毒性表皮坏死松解症患者护理的回顾性分析[J].皮肤性病诊疗学杂志,2024,31(8):546-550,5.基金项目
广东省自然科学基金(2024A151503129) （2024A151503129）
广东省中医药课题(20231190) （20231190）
