岭南现代临床外科2024，Vol.24Issue(3)：141-149,9.DOI:10.3969/j.issn.1009-976X.2024.03.001
增强CT细胞外体积分数预测胰腺癌术后患者预后
Prediction of prognosis of pancreatic cancer patients after operation by enhanced CT extracellu-lar volume fraction
摘要
Abstract
Objective To explore the prognostic value of extracellular volume fraction(ECVf)in patients with pancreatic cancer after operation.Methods A total of 66 patients with pancreatic cancer who underwent surgical treatment in Sun Yat-Sen Memorial Hospital of Sun Yat-sen University from January 2014 to December 2022 were selected.The multi-detectorrow CT scanner was used for multi-phase enhanced CT scanning,and the images of the non-contrasted phase and equilibration phase were obtained.The ECVf of pancreatic cancer lesions was calculated by formula.According to the median ECVf,the patients were divided into high ECVf group and low ECVf group.The prognosis of the two groups was analyzed,and a nomogram model was established to predict the prognosis of patients with pancreatic cancer treated after operation.Results The high ECVf group had longer OS(P=0.002)and DFS(P=0.024)than the low ECVf group.The median OS of high ECVf group and low ECVf group were 32.0 months and 20.3 months respectively,and the median DFS were 20.7 months and 12.3 months,respectively.The area under curve(AUC)of nomogram model for predicting 1-year,2-year and 3-year survival rates were 0.854,0.802 and 0.707,respectively.Conclusion ECVf can be used as a prognostic indicator for patients with pancreatic cancer after operation.关键词
胰腺导管腺癌/细胞外体积分数/电子计算机断层扫描/预后Key words
pancreatic ductal adenocarcinoma/extracellular volume fraction/computed tomogram/prognosis分类
医药卫生引用本文复制引用
刘立强,李文滨,叶会霖..增强CT细胞外体积分数预测胰腺癌术后患者预后[J].岭南现代临床外科,2024,24(3):141-149,9.基金项目
国家自然科学基金青年基金项目(82003073) （82003073）
广东省自然科学基金面上项目(2020A1515011296) （2020A1515011296）
