岭南现代临床外科2024，Vol.24Issue(3)：193-198,6.DOI:10.3969/j.issn.1009-976X.2024.03.008
不同剂量右美托咪定鞘内应用对PPH术后舒适化治疗效果的影响
Effect of intrathecal application of different doses of dexmedetomidine on postoperative comfort treatment of PPH
摘要
Abstract
Objective To explore the effect of intrathecal application of different doses of dexmedeto-midine on postoperative analgesia during procedure for prolapse and hemorrhoids(PPH).Methods 380 patients undergoing PPH under combined spinal and epidural anesthesia were selected and randomly divided into 4 groups:C group(intrathecal 0.5%ropivacaine 15 mg),LDA group(intrathecal 0.5%ropivacaine 15 mg+dexmedetomidine 5 μg),LDB group(intrathecal 0.5%ropivacaine 15 mg+dexme-detomidine 7.5 μg)and LDC group(intrathecal 0.5%ropivacaine 15 mg+dexmedetomidine 10 μg),95 cases in each group.Record the time when patients first used analgesics,spinal anesthesia analgesia time,and differential analgesia time after surgery,and the visual analog scale(visual analogue scale,VAS)score.Results The first postoperative analgesic time,spinal anesthesia analgesia time,and differential analgesia time in the LDA group,LDB group,and LDC group were all longer than those in the C group,and the differences were statistically significant(P<0.05).The VAS scores of the LDA group,LDB group,and LDC group at rest and during activity at 6 h,12 h,and 24 h after surgery and immediately after taking analgesics were lower than those in the C group,and the difference was statistically significant(P<0.05).Conclusion Dexmedetomidine is an intrathecal safe and effective adjuvant,which can enhance the effect of postoperative analgesia and reduce the dosage and frequency of postoperative analgesics.It is an effective scheme to realize comfortable medical treatment after PPH,Intrathecal ap-plication of 7.5 μg dexmedetomidine can achieve more satisfactory differential analgesia time.关键词
右美托咪定/鞘内注射/PPH/舒适化医疗Key words
dexmedetomidine/intrathecal injection/PPH/comfortable medical care分类
医药卫生引用本文复制引用
覃福兴,黄泽汉..不同剂量右美托咪定鞘内应用对PPH术后舒适化治疗效果的影响[J].岭南现代临床外科,2024,24(3):193-198,6.基金项目
百色市科学研究与技术开发计划项目(百科20232078) （百科20232078）
