老年医学与保健2024，Vol.30Issue(4)：925-929,940,6.
老年慢加亚急性肝衰竭患者SIRI、SII、肝纤维化水平特征与不良预后的相关性研究
Study on correlation between SIRI,SII,liver fibrosis level and poor prognosis in elderly patients with chronic and subacute liver failure
尤丽 1韩丽1
作者信息
- 1. 中国医科大学附属盛京医院第二感染性疾病、肝病病房,辽宁沈阳 110022
- 折叠
摘要
Abstract
Objective To investigate the correlation between systemic inflammation response index(SIRI),systemic immune-inflammation index(SII),liver fibrosis level and poor prognosis in elderly patients with chronic and subacute liver failure.Methods A total of 105 elderly patients with chronic and subacute liver failure admitted to Shengjing Hospital Affilia-ted to China Medical University from March 2019 to June 2023 were selected as the study subjects.They were divided into good prognosis group(n=72)and poor prognosis group(n=33)according to their prognosis after treatment.The SIRI,SII and liver fibrosis factor 4 index(FIB-4)were compared between the two groups.Binary logistic regression analysis was used to screen the important risk factors for poor prognosis in elderly patients with chronic and subacute liver failure.Results The lev-els of alanine aminotransferase,aspartate aminotransferase,SIRI,SII and FIB-4 in the poor prognosis group were significantly higher than those in the good prognosis group,and the lymphocyte count was significantly lower than that in the good prognosis group(all P＜0.05).Univariate and multivariate Logistic regression analysis showed that high levels of SIRI,SII,and FIB-4 were important risk factors for elderly patients with chronic and subacute liver failure(P＜0.05).Conclusion SIRI,SII and FIB-4 can be used as potential biological markers to evaluate the prognosis of elderly patients with chronic and subacute liver failure,which provides a basis for further construction of prognostic risk prediction models.关键词
老年/慢加亚急性肝衰竭/全身炎症反应指数/预后Key words
elderly/chronic and subacute liver failure/systemic inflammation response index/prognosis引用本文复制引用
尤丽,韩丽..老年慢加亚急性肝衰竭患者SIRI、SII、肝纤维化水平特征与不良预后的相关性研究[J].老年医学与保健,2024,30(4):925-929,940,6.
