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经尿道前列腺电切术与经尿道柱状水囊前列腺扩开术治疗老年良性前列腺增生的比较研究OACSTPCD

A comparative study of TUCBDP and TURP in treatment of benign prostatic hyperplasia in elderly patients

中文摘要英文摘要

目的 分析老年良性前列腺增生(BPH)治疗中,经尿道前列腺电切术(TURP)与经尿道柱状水囊前列腺扩开术(TUCBDP)的疗效差异,旨在为该病症提供更科学的治疗策略.方法 回顾性分析2021年2月-2024年2月青岛市胶州中心医院收治的150例老年BPH患者的临床资料,依据手术方式的不同分为TUCBDP组78例和TURP组72例,经倾向性评分匹配以1:1比例,最终纳入基线均衡的2组,每组67例.分析2组围手术期与并发症情况.于术前及术后90 d,比较2组尿动力学指标[峰值排尿流速(Qmax)、尿后膀胱剩余量(RUV)、膀胱顺应程度(BC)、最大尿道闭合压(Pdet.max)]和疾病转归[采用国际前列腺症状评分(IPSS)、BPH生活质量量表(BPHQLS)评估].结果 与TURP组相比,TUCBDP组的手术时长、尿管插置期限、膀胱灌洗时长、留院时长更短,手术失血量更少(均P<0.05).术后90 d,2组Qmax、BC均较同组术前升高,且TUCBDP组Qmax、BC均高于TURP组(P<0.05);2组RUV、Pdet.max均较同组术前降低,与TURP组相比,TUCBDP组RUV、Pdet.max的降幅更大(P<0.05);2组IPSS、BPHQLS评分均低于同组术前,且TUCBDP组上述评分的降幅更大(P<0.05).TUCBDP组术后并发症发生率明显低于TURP组(P<0.05).随访期内,2组复发率差异无统计学意义(P>0.05).结论 相比TURP术,TUCBDP术治疗的老年BPH患者围手术期指标改善效果更为显著,并且在促进排尿功能恢复、减少前列腺症状、提高生活质量和安全性等方面具有优势,但对远期疗效可能无影响.

Objective To analyze the difference between transurethral resection of the prostate(TURP)and transure-thral columnar balloon dilation of the prostate(TUCBDP)in the treatment of benign prostatic hyperplasia(BPH)in the elder-ly,and provide a more scientific treatment strategy for the disease.Methods The clinical data of 150 elderly BPH patients ad-mitted to Jiaozhou Central Hospital of Qingdao City from February 2021 to February 2024 was retrospectively analyzed.Ac-cording to the different surgical methods,they were divided into TUCBDP group(78 cases)and TURP group(72 cases).Af-ter propensity score matching at a ratio of 1:1,patients with baseline balance were finally included in the two groups,with 67 cases in each group.The perioperative conditions and complications of the two groups were analyzed.Before and 90 days after surgery,urodynamic indicators[maximal urinary flow rate(Qmax),residual urine volume(RUV),bladder compliance(BC),maximal detrusor pressure(Pdet.max)]and disease outcomes[International Prostate Symptom Score(IPSS)and Quality of Life Scale for BPH patients(BPHQLS)score]were compared between the two groups.Results Compared with the TURP group,the surgical time,urinary catheter indwelling time,bladder irrigation time and hospital stay in the TUCBDP group were shorter,and the intraoperative blood loss was less(P<0.05).90 days after surgery,the Qmax and BC in the two groups were higher than those of the same group before surgery,and the Qmax and BC in the TUCBDP group were higher than those in the TURP group(P<0.05);the RUV and Pdet.max in the two groups were lower than those in the same group before surgery,and the RUV and Pdet.max in the TUCBDP group were lower than those in the TURP group(P<0.05);the scores of IPSS and BPHQLS in the two groups were lower than those in the same group before surgery,and the above scores in the TUCB-DP group decreased more significantly(P<0.05).The incidence of postoperative complications in the TUCBDP group were sig-nificantly lower than that in the TURP group(P<0.05).During the follow-up period,there was no significant difference in the recurrence rate between the two groups(P>0.05).Conclusion Compared with TURP,TUCBDP has more significant im-provement in perioperative indicators in elderly patients with BPH.It has advantages in promoting the recovery of urinary func-tion,reducing prostate symptoms,improving quality of life and safety,but it may have no effect on long-term outcomes.

栾杰;韩月欣;王培耕

青岛市胶州中心医院泌尿外科,山东青岛 266300

老年良性前列腺增生经尿道柱状水囊前列腺扩开术经尿道前列腺电切术

elderlybenign prostatic hyperplasiatransurethral columnar balloon dilation of the prostatetransurethral resection of the prostate

《老年医学与保健》 2024 (004)

981-984,1040 / 5

青岛市医药卫生科研指导项目(2017-WJZD094)

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