老年医学与保健2024，Vol.30Issue(4)：1078-1083,6.
持续血糖监测评估的目标范围内时间与老年2型糖尿病患者蛋白尿的相关性研究
A study of relationship between time in target range assessed by continuous glucose monitoring and proteinuria in elderly patients with type 2 diabetes mellitus
摘要
Abstract
Objective To explore the relationship between time in target range(T1R)assessed by continuous glucose mo-nitoring and proteinuria in elderly patients with type 2 diabetes mellitus(T2DM).Methods The clinical data of 176 elderly T2DM patients hospitalized in Eighth People's Hospital of Shanghai City from October 2016 to August 2020 were retrospectively analyzed.The patients were divided into normal albuminuria group(n=99),microalbuminuria group(n=51),and macroalbu-minuria group(n=26)based on their urinary microalbumin/creatinine ratio.The general data and continuous blood glucose monitoring indexes of the 3 groups were compared.Spearman correlation coefficient analysis and multiple ordinal regression analysis were used to analyze the relationship between TIR quartile and the severity of diabetes albuminuria.Results There were significant differences among the three groups in gender,T2DM course,hypertension constituent ratio,smoking histo-ry,use of insulin,use of angiotensin converting enzyme inhibitor and angiotensin Ⅱ receptor blocker,use of statins,systolic blood pressure,total cholesterol,low-density lipoprotein cholesterol,estimated glomerular filtration rate,mean amplitude of glycemic excursion,TIR and prevalence of diabetes retinopathy(P＜0.05).The quartiles of TIR were negatively correlated with the severity of proteinuria.The higher the TIR,the lower the risk of developing proteinuria in elderly T2DM patients.Conclusion TIR may be associated with the risk and severity of proteinuria in elderly T2DM patients.关键词
老年/2型糖尿病/持续血糖监测/目标范围内时间/蛋白尿Key words
elderly/type 2 diabetes mellitus/continuous glucose monitoring/time in target range/proteinuria引用本文复制引用
宋静,卢叶,王文婕,李丽,杜炜,万静..持续血糖监测评估的目标范围内时间与老年2型糖尿病患者蛋白尿的相关性研究[J].老年医学与保健,2024,30(4):1078-1083,6.基金项目
徐汇区医学科研课题(SHXH201329) （SHXH201329）
