内科理论与实践2024，Vol.19Issue(3)：185-187,3.DOI:10.16138/j.1673-6087.2024.03.06
CEBPA双突变合并GATA2种系突变急性髓系白血病1例
Acute myeloid leukemia with CEBPA double mutation combined with GATA2 germline mutation:one case report
摘要
Abstract
The patient was diagnosed as acute myeloid leukaemia with CEBPA double mutation,GATA2 and IKZF1 mutation in 2021,and relapsed after giving two courses of IA treatment(idarubicin,cytosine arabinoside).There was transient remission after four additional courses of azacitidine combined with venetoclax.The patient relapsed again due to lack of regular treatment.This paper mainly analyses the therapeutic and prognostic role of CEBPA double mutation combined with GATA2 germline mutation in acute myeloid leukaemia.关键词
GATA2突变/急性髓系白血病/造血干细胞移植/血液系统恶性疾病/CEBPAKey words
GATA2 mutation/Acute myeloid leukaemia/Haematopoietic stem cell transplantation/Haematological malignancies/CEBPA分类
医药卫生引用本文复制引用
安慧慧,吴涛,李芸芸,刘文慧,田思锐,刘洋,高铭敏..CEBPA双突变合并GATA2种系突变急性髓系白血病1例[J].内科理论与实践,2024,19(3):185-187,3.基金项目
甘肃省科技计划(创新基地和人才计划)项目(21JR7RA015) （创新基地和人才计划）
甘肃省科技计划项目(22YF7FA106) （22YF7FA106）
联勤保障部队第九四〇医院科研项目(2021yxky078) （2021yxky078）
