布地奈德联合鼻内镜腺样体切除术治疗鼻窦炎和鼻息肉患者的效果分析OA
Effect Analysis of Budesonide Combined with Endoscopic Adenoidectomy in the Treatment of Sinusitis and Nasal Polyps Datients
目的:分析对鼻窦炎和鼻息肉患者实施布地奈德联合鼻内镜腺样体切除术治疗的效果.方法:选取 2021年 6月—2023年 6月山阳县人民医院收治的 80例鼻窦炎和鼻息肉患者为研究对象,根据随机抽样法将患者分为对照组和研究组,各 40例.对照组实施生理盐水联合鼻内镜腺样体切除术治疗,研究组实施布地奈德联合鼻内镜腺样体切除术治疗,比较两组的治疗总有效率、鼻腔功能、炎症反应、不良反应发生情况.结果:研究组治疗总有效率为 95.00%,高于对照组的80.00%,差异有统计学意义(P<0.05).治疗后,研究组的嗅觉功能评分、Lund-Kennedy评分、Lund-Mackey评分、IL-6 水平、TNF-α水平均低于对照组,差异均有统计学意义(P<0.05).研究组不良反应发生率为 5.00%,低于对照组的 10.00%,但两组的不良反应发生率比较,差异无统计学意义(P>0.05).结论:对鼻窦炎和鼻息肉患者实施布地奈德联合鼻内镜腺样体切除术,治疗效果好,在改善鼻腔功能及减轻炎症方面作用明显,具有一定安全性.
Objective:To analyze the therapeutic effect of Budesonide combined with endoscopic adenoidectomy in patients with sinusitis and nasal polyps.Methods:A total of 80 patients with sinusitis and nasal polyps treated in Shanyang County People's Hospital from June 2021 to June 2023 were selected as the study objects,and were divided into a control group and a study group according to random sampling method,with 40 cases in each group.The control group was treated with normal saline combined with nasal endoscopic adenoidectomy,and the study group was treated with Budesonide combined with nasal endoscopic adenoidectomy.The efficacy,nasal function,inflammatory response and adverse reactions of the two groups were compared.Results:The therapeutic effect of the study group was 95.00%,which was higher than 80.00%of.the control group,the difference was statistically significant(P<0.05).After treatment,the olfactory function score,Lund-Kennedy score,Lund-Mackey score,IL-6 level and TNF-α level in the study group were lower than those in the control group,with statistical significance(P<0.05).The incidence of adverse reactions in the study group was 5.00%,which was lower than 10.00%in the control group,but there was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion:Budesonide combined with endoscopic adenoidectomy in patients with sinusitis and nasal polyps has a good therapeutic effect,which is significant in improving nasal function and alleviating inflammation,with certain security.
肖淑芳;敬怡
陕西省山阳县人民医院耳鼻咽喉科,陕西 商洛 726400
临床医学
鼻窦炎鼻息肉布地奈德鼻内镜腺样体切除术
SinusitisNasal polypsBudesonideNasal endoscopyAdenoidectomy
《中国伤残医学》 2024 (013)
4-7 / 4
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