中国伤残医学2024，Vol.32Issue(13)：22-25,4.DOI:10.13214/j.cnki.cjotadm.2024.013.007
成人慢性呼吸系统疾病急性加重频率与锌缺乏关系的研究分析
Study on the Relationship Between Acute Exacerbation Frequency of Chronic Respiratory Diseases and Zinc Deficiency in Adults
摘要
Abstract
Objective:To investigate the relationship between zinc deficiency and acute exacerbation freguency of chronic respiratory diseases in adults.Methods:A total of 49 respiratory and critical care patients treated in the Nanhai District Seventh People's Hospital of Foshan City from January 2022 to December 2023 were retrospectively selected as the study objects,and were divided into an experimental group(n=26)and a control group(n=23)according to medical records and auxiliary examination results.The experimental group was chronic respiratory disease patients,and the control group was non-chronic respiratory disease patients.The serum zinc content of the two groups was measured,and the two groups were divided into a zinc deficiency subgroup and a zincnormal subgroup according to the results.The number of respiratory tract infections that required antibiotic or antiviral intervention during the study period was counted(hereinafter referred to as the number of acute infections).Results:Among the 49 patients,39 cases(79.59%)had a total zinc deficiency.In the experimental group,there were 4 cases(15.38%)of zinc deficiency and 17 cases(65.38%)of marginal zinc deficiency.There were 8 cases(34.78%)of zinc deficiency in control group and 10 cases(43.48%)of marginal zinc deficiency.There were no statistical significances in zinc deficiency between the two groups(P>0.05).The number of acute infection in experimental group was higher than that in control group,the difference was statistically significant(P<0.05).The infection frequency of zinc deficiency subgroup was higher than that of normal zinc subgroup,the difference was statistically significant(P<0.05).There was no significant difference in infection frequency zincbetween deficiency subgroup and zinc normal subgroup(P>0.05).Conclusion:Zinc deficiency can lead to the decline of immunity,and then easy to cause respiratory infection,which is especially obvious in patients with chronic respiratory diseases.In the daily management of patients with chronic respiratory diseases,more attention should be paid to maintaining the homeostasis of trace element zinc.关键词
慢性呼吸系统疾病/锌缺乏/边缘性缺锌Key words
Chronic respiratory diseases/Zinc deficiency/Marginal zinc deficiency分类
医药卫生引用本文复制引用
梁捷恒,邓蕴琦,傅志钢,冼小玲,邓军丽..成人慢性呼吸系统疾病急性加重频率与锌缺乏关系的研究分析[J].中国伤残医学,2024,32(13):22-25,4.基金项目
佛山市卫生健康局医学科研课题(20220142) （20220142）
