碘解磷定注射液急诊治疗农药中毒患者的效果分析OA
Effect Analysis of Proxime Iodide Injection in Emergency Treatment of Patients with Pesticide Poisoning
目的:探讨碘解磷定注射液急诊治疗农药中毒患者的效果.方法:选取 2022年 3月—2024年 3月松原市中心医院收治的 90例农药中毒患者为研究对象,按照随机数字表法将患者分为对照组与研究组,每组45例.所有患者均行体表农药清理、洗胃、导泻、补充电解质,对照组采用硫酸阿托品注射液治疗,研究组在对照组基础上采用碘解磷定注射液治疗.比较两组的临床疗效、胆碱酯酶活性恢复正常时间、住院时间及神经功能.结果:研究组治疗总有效率为 95.56%,高于对照组的 82.22%,差异有统计学意义(P<0.05).研究组胆碱酯酶活性恢复正常时间、住院时间均短于对照组,差异均有统计学意义(P<0.05).治疗 7 d后,研究组运动神经传导速度和感觉神经传导速度均快于对照组,差异均有统计学意义(P<0.05).结论:急诊治疗农药中毒患者中进行碘解磷定静脉输注可提升临床疗效,缩短恢复正常时间且可改善神经功能.
Objective:To investigate the effect of proxime iodide injection in emergency treatment of patients with pesticide poisoning.Methods:A total of 90 patients with pesticide poisoning admitted to Songyuan Central Hospital from March 2022 to March 2024 were selected as the study objects.According to random number table method,the patients were divided into a control group and a study group,with 45 cases in each group.All patients were treated with body surface pesticide cleaning,gastric lavage,catharsis and electrolyte supplementation.The control group was treated with atropine sulfate injection,and the study group was treated with proxime iodide injection on the basis of the control group.The clinical efficacy,recovery time of cholinesterase activity,length of hospital stay and nerve function of the two groups were compared.Results:The total effective rate of the study group was 95.56%,which was higher than 82.22%of the control group,the difference was statistically significant(P<0.05).The recovery time of cholinesterase activity and hospital stay in the study group were shorter than those in the control group,the differences were statistically significant(P<0.05).Seven days after treatment,the motor nerve conduction velocity and sensory nerve conduction velocity of the study group were faster than those of the control group,the differences were statistically significant(P<0.05).Conclusion:Intravenous infusion of pralidoxime iodide in emergency treatment of patients with pesticide poisoning can improve clinical efficacy,shorten recovery time and improve neurological function.
张春风
吉林省松原市中心医院(松原市儿童医院)急诊科,吉林 松原 138000
临床医学
农药中毒碘解磷胆碱酯酶神经功能
Pesticide poisoningIodine phosphate hydrolysisCholinesteraseNeurological function
《中国伤残医学》 2024 (013)
30-32 / 3
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