成都市龙泉驿地区城市居民结直肠癌筛查结果分析OACSTPCD

Objective:To analyze the community resi-dents'colonoscopy screening results of the Urban Cancer Ear-ly Diagnosis and Treatment Project in Longquanyi District of Chengdu,and provide a basis for evaluating and optimizing colorectal cancer screening strategies.Methods:A total of 1,591 urban community residents who were confirmed to be positive in primary screening of colorectal cancer in the Urban Cancer Early Diagnosis and Treatment Project in the Longquanyi District of Chengdu from September 2019 to October 2023,and who completed diagnostic colonoscopy and ob-tained pathological examination results in our hospital were selected as the research subjects.According to the diagnostic results of colonoscopy,the research subjects were assigned to the lesion group and the normal group.The lesion group were further divided into three groups,the colorectal cancer group,the precancerous lesion group and the benign lesion group based on the pathological results.The differences in sex and age among groups were analyzed.Results:A total of 1,591 positive individuals in primary screening were included in this study,including 915 cases in the normal group and 626 cases in the lesion group according to colonoscopic diagnosis.The lesion detection rate was 39.35％,and it was signifi-cantly higher in males than in females(47.27％vs 32.88％,x2=34.187,P＜0.001).As age increases,the detec-tion rate of lesions shows an upward trend(x2trends=32.432,P＜0.001),and after stratification by gender,there was a statistically significant upward trend in it for both men and women(all P＜0.05).From 2019 to 2023,the detection rate of lesions shows an upward trend(x2trends=75.757,P＜0.001),and after stratification by gender,there was a sta-tistically significant upward trend in it for both men and women(all P＜0.05).In the pathologically diagnosed(by colonoscopy)626 cases,there were 3 cases of colorectal cancer,with a detection rate of 0.19％,228 cases of precan-cerous lesions,with a detection rate of 14.33％,and 395 cases of benign lesions,with a detection rate of 24.83％.The detection rate of precancerous lesions was highest in the 60 to 69 age group,and the detection rate of benign lesions was highest in the over 70-year age group,and the differences were statistically significant(all P＜0.05).Conclusion:The colorectal cancer screening for community residents in current Urban Cancer Early Diagnosis and Treatment Project can effectively identify high-risk groups,accurately detect colorectal cancer and precancerous lesions,and is an important secondary prevention measure for controlling the incidence and mortality of colorectal cancer,providing solid scientific evi-dence for public health strategies.