肿瘤预防与治疗2024，Vol.37Issue(8)：691-697,7.DOI:10.3969/j.issn.1674-0904.2024.08.008
非编码RNA介导的自噬在卵巢癌中的研究进展
Advances in Roles of Non-coding RNAs-Mediated Autophagy in Ovarian Cancer
摘要
Abstract
Non-coding RNA(ncRNA)is a factor that regulates biological processes and plays an important role in the bi-ological behaviors of tumor.NcRNA can act as competing endogenous RNA and RNA-binding proteins in tumors,participat-ing in the regulation of cellular transcription and translation.Autophagy,a process of self-engulfing excess content and pro-ducing new molecules to maintain cell homeostasis,has dual roles in ovarian cancer(OC)which needs to be deeply dis-cussed.NcRNA can mediate the changes in biological behaviors of OC through autophagy-related proteins and signaling path-ways.Meanwhile,autophagy has many classifications,and this paper focuses on the classical macroautophagy.We explore the crosstalk relationship between ncRNA(miRNA,lncRNA and circRNA)and autophagy in OC,which is helpful to pro-vide a treatment strategy for OC based on ncRNA and autophagy.关键词
非编码RNA/卵巢癌/自噬/信号通路Key words
Non-coding RNA/Ovarian cancer/Autophagy/Signaling pathway分类
医药卫生引用本文复制引用
叶宛鹭,鲁艳明..非编码RNA介导的自噬在卵巢癌中的研究进展[J].肿瘤预防与治疗,2024,37(8):691-697,7.基金项目
辽宁省自然科学基金(编号:2019-ZD-0790) This study was supported by Natural Science Foundation of Liaoning Province(No.2019-ZD-0790). （编号:2019-ZD-0790）
