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中性粒细胞的异质性和多潜能性在肿瘤进展中的作用

李玫颖 曹邦荣 梁胜梅 马士淇

肿瘤预防与治疗2024,Vol.37Issue(8):698-704,7.
肿瘤预防与治疗2024,Vol.37Issue(8):698-704,7.DOI:10.3969/j.issn.1674-0904.2024.08.009

中性粒细胞的异质性和多潜能性在肿瘤进展中的作用

Heterogeneity and Pluripotency of Neutrophils in the Progression of Tumors

李玫颖 1曹邦荣 1梁胜梅 1马士淇1

作者信息

  • 1. 610041 成都,四川省肿瘤临床医学研究中心,四川省肿瘤医院·研究所,四川省癌症防治中心,电子科技大学附属肿瘤医院实验研究部
  • 折叠

摘要

Abstract

Neutrophils are the most abundant myeloid cells in human blood and play a potential role in the occurrence and development of tumors.Neutrophils are characterized by a short life span,terminal differentiation,and non-proliferative properties,and their significance for tumor progression requires further investigating.In recent years,multiple studies have found that neutrophils exhibit heterogeneity and multipotency within the tumor microenvironment.This review summarizes the factors affecting tumor progression due to the heterogeneity and multipotency of neutrophils and their interaction with tumor cells,providing a potential theoretical basis for tumor treatment strategies targeting neutrophils.

关键词

中性粒细胞/肿瘤微环境/异质性/多潜能性

Key words

Neutrophils/Tumor microenvironment/Heterogeneity/Pluripotency

分类

医药卫生

引用本文复制引用

李玫颖,曹邦荣,梁胜梅,马士淇..中性粒细胞的异质性和多潜能性在肿瘤进展中的作用[J].肿瘤预防与治疗,2024,37(8):698-704,7.

基金项目

国家自然科学基金青年项目(编号:82303645) This study was supported by National Natural Science Foundation of China(No.82303645). (编号:82303645)

肿瘤预防与治疗

OACSTPCD

1674-0904

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