陕西中医2024，Vol.45Issue(9)：1190-1194,5.DOI:10.3969/j.issn.1000-7369.2024.09.008
甲状腺功能亢进患者的中医症型分布特点及与甲功、血脂相关性分析
The distribution characteristics of TCM syndromes in hyperthyroidism and the correlation analysis with thyroid function and blood lipid
摘要
Abstract
Objective:To analyze the distribution characteristics of TCM symptoms of hyperthyroidism and its correlation with thyroid function and lipid index.Methods:A total of 178 hyperthyroidism patients(hyperthyroidism group)were selected for the study.At the same time,80 healthy subjects(set as control group)were selected for comparison.The clinical data and laboratory results of the two groups were compared.To analyze the common types,clinical symptoms and signs of Chinese medicine syndrome of hyperthyroidism patients.To further explore the corre-lation between TCM common witness type and blood lipid and thyroid function index.Results:After analysis,there were no significant differences in age,sex,drinking and smoking history,triglyceride(TG)and low density lipopro-tein cholesterol(LDL-C)levels between the two groups(P>0.05).In the hyperthyroidism group,thyroxine(FT3),thyroxine(FT4),total triiodothyronine(TT3),total thyroxine(TT4),anti-thyroid peroxidase antibody(TPOAb),anti-thyroglobulin antibody(TGAb),total cholesterol(TC),TG and high-density lipoprotein cholesterol(HDL-C)were detected,body mass index(BMI)levels were higher than those of control group(P<0.05);The level of thy-roid stimulating hormone(TSH)in hyperthyroidism group was lower than that in control group(P<0.05).Among 178 patients,the top three syndrome-type frequency from high to low were sanyin-yang deficiency cold syndrome,Shaoyang loss of hub syndrome,gallbladder fire internal depression syndrome,Shaoyang cold heat mixed syndrome.The three clinical symptoms with high frequency in patients with hyperthyroidism are fatigue,irritability and hyper-hidrosis.The top three common signs of hyperthyroidism were goiter,exophthalmic sign and thyroid nodule.After variable screening,the main influencing factors were obtained.It was concluded that FT3,FT4 and TGAb levels were positively correlated with sanyang deficiency cold syndrome,FT3 and TPOAb levels were positively correlated with Shaoyang loss of Shu and bile fire internal depression syndrome,and TSH levels were negatively correlated with them.FT3,FT4,TGAb and TC were positively correlated with Shaoyang cold and heat mixed syndrome,and TSH level was negatively correlated with it.The other indicators were not found to be correlated with the traditional Chi-nese medicine witness type.Conclusion:The common TCM syndrome types in patients with hyperthyroidism are three Yin and Yang deficiency cold syndrome,Shaoyang loss of hub,gallbladder fire internal depression syndrome,Shaoyang cold and heat mixed syndrome.The common clinical symptoms are fatigue,irritability,hyperhidrosis,and common signs are goiter,eye protrusion sign,thyroid nodules.FT3,FT4,TGAb,TC,TPOAb bare closely related to the common types of Chinese medicine,and have reference value in clinical diagnosis and treatment of hyperthyroidism.关键词
甲状腺功能亢进/中医证型/临床症状/相关性/辨证/瘿病Key words
Hyperthyroidism/TCM syndrome type/Clinical symptoms/Relevance/Dialectical/Gall disease分类
医药卫生引用本文复制引用
何逸俊,魏华..甲状腺功能亢进患者的中医症型分布特点及与甲功、血脂相关性分析[J].陕西中医,2024,45(9):1190-1194,5.基金项目
广东省科技厅重大项目(2014B010118005) （2014B010118005）
广东省部共建中医湿证国家重点实验室项目(SZ2021ZZ3203) （SZ2021ZZ3203）
