陕西中医2024,Vol.45Issue(9):1199-1202,4.DOI:10.3969/j.issn.1000-7369.2024.09.010
滋阴降糖方治疗2型糖尿病疗效及对患者血糖波动相关指标、胰岛功能的影响
Effect of Ziyin Jiangtang recipe on type 2 diabetes mellitus and its influence on blood glucose fluctuation and islet function
摘要
Abstract
Objective:To explore the therapeutic effect of Ziyin Jiangtang recipe on type 2 diabetes mellitus(T2DM).Methods:122 patients with T2DMs were divided into the control group(61 cases)and the observation group(61 cases)by the random number table method.The control group received routine western medicine treat-ment,while the observation group received Ziyin Jiangtang recipe on the basis of the control group.Both groups con-tinued treatment for 1 month.The clinical efficacy,including traditional Chinese medicine syndrome scores,blood glu-cose fluctuation related indicators,pancreatic islet function,and blood lipid indicators between two groups were com-pared.Results:The rate of total effective in the observation group after treatment was higher than the control group(P<0.05).Compared with before treatment,after treatment,the levels of blood glucose fluctuation related indicators of both groups decreased,and compared with the control group,the observation group was lower(P<0.05).Com-pared with before treatment,after treatment,the levels of serum fasting insulin(FINS)in both groups decreased,and compared with the control group,the observation group was lower;Insulin sensitivity index(ISI),pancreatic islets β cell function index(HOMA-β)in both control group increased,and compared with the control group,the observation group was higher(P<0.05).Compared with before treatment,after treatment,the levels of serum triglycerides(TG),low-density lipoprotein cholesterol(LDL-C),total cholesterol(TC)in both groups decreased,and compared with the control group,the observation group was lower;The levels of serum high-density lipoprotein cholesterol(HDL-C)were all elevated,and compared with the control group,the observation group was higher(P<0.05).Con-clusion:Ziyin Jiangtang recipe could improve the function of pancreatic islets of patients with T2DM,improve blood glucose fluctuations and blood lipid indicators,and then improve the treatment effect.关键词
2型糖尿病/滋阴降糖方/血糖波动/胰岛功能/血脂指标/中医证候积分Key words
Type 2 diabetes/Ziyin Jiangtang recipe/Blood glucose fluctuations/Islet function/Blood lipid indi-cators/Traditional Chinese medicine syndrome points分类
医药卫生引用本文复制引用
沈伟,胡军平,黄昌秀..滋阴降糖方治疗2型糖尿病疗效及对患者血糖波动相关指标、胰岛功能的影响[J].陕西中医,2024,45(9):1199-1202,4.基金项目
安徽省重点研究与开发计划立项课题(202104J07020014) (202104J07020014)