同济大学学报（医学版）2024，Vol.45Issue(4)：550-556,7.DOI:10.12289/j.issn.2097-4345.24038
预后营养指数对新疆喀什地区糖尿病足患者全因死亡的预测价值
Prognostic nutritional index in predicting survival for patients with diabetic foot ulcer in kashgar District of Xinjiang
摘要
Abstract
Objective To investigate the predictive value of prognostic nutritional index(PNI)for all-cause mortality in patients with diabetic foot.Methods Clinical data of 132 patients aged 60.5±10.02 years(89 were males)with diabetic foot admitted to the Department of Endocrinology of the Second People's Hospital of Kashgar from January 2018 to December 2019 were retrospectively analyzed.An annual telephone follow-up was conducted for all patients after discharge.During 3 years of follow-up 78 patients survived(survival group)and 54 patients died(fatal group).Based on the best cut-off value of PNI,there were 86 cases in the high PNI group(PNI≥41.62)and 46 cases in the low PNI group(PNI＜41.62).Kaplan-Meier method was used to compare the survival rate of the two groups,and Cox proportional hazards model was used to explore the relationship between PNI and all-cause death in patients with diabetic foot.Results Log-rank test showed that the overall survival rate was lower in the low PNI group(P＜0.001).Multivariate Cox regression analysis showed that PNI,coronary heart disease,and severe ulcer were independently associated with all-cause death in patients with diabetic foot(P＜0.05).ROC curve analysis showed that the AUC of PNI for predicting all-cause mortality in patients with diabetic foot was 0.798(95% CI:0.721-0.875,P＜0.000 1),the best cut-off value was 41.62 with a sensitivity of 61.1% and specificity of 83.3% .Conclusion Higher PNI is associated with lower mortality in patients with diabetic foot,and PNI may be able to predict all-cause mortality in patients with diabetic foot in kashgar District of Xinjiang.关键词
预后营养指数/糖尿病足/全因死亡Key words
prognostic nutritional index/diabetic foot/all-cause mortality分类
医药卫生引用本文复制引用
伊尔番·阿不都艾尼,唐兆生,王华..预后营养指数对新疆喀什地区糖尿病足患者全因死亡的预测价值[J].同济大学学报（医学版）,2024,45(4):550-556,7.基金项目
上海市浦东新区卫生系统学科带头人培养计划(PWRd2018-02) （PWRd2018-02）
