生命科学仪器2024，Vol.22Issue(4)：73-75,3.DOI:10.11967/2024220825
支气管镜肺泡灌洗辅助治疗对重症肺炎患儿血清YKL-40、sIL-2R、Copeptin水平的影响
Effect of Bronchoscopic Alveolar Lavage on Serum YKL-40、sIL-2R And Copeptin Levels in Children with Severe Pneumonia And Analysis of Prognostic Risk Factors
季鹏 1张云2
作者信息
- 1. 常州市第二人民医院儿科,江苏常州 213000
- 2. 常州市第一人民医院儿科,江苏常州 213000
- 折叠
摘要
Abstract
Objective:To study and analyze the effects of bronchoalveolar lavage(BAL)on serum levels of chitinase protein 40(YKL-40)、soluble interleukin-2 receptor(sIL-2R)and peptide(Copeptin)in children with severe pneumonia(SP).Methods:Eighty-one children with SP from December 2021 to December 2023 were randomly divided into lavage group(n=40)and routine group(n=41).Routine treatment was carried out in the routine group,and BAL treatment was supplemented in the lavage group on the basis of routine treatment.The clinical ef-ficacy、serum levels of YKL-40、sIL-2R and Copeptin were compared between the two groups.Results:The total effective rate of lavage group was higher than that of routine group,P<0.0).After treatment,the serum levels of YKL-40、sIL-2R and Copeptin in lavage group were lower than those in routine group,P<0.05.Conclusion:BAL is effective in adjuvant treatment of children with SP,and can negatively regulate the serum levels of YKL-40、sIL-2R and Copeptin.关键词
重症肺炎/支气管镜肺泡灌洗/甲壳质酶蛋白40/可溶性白细胞介素-2受体/和肽素Key words
Severe pneumonia/Bronchoscopic alveolar lavage/Chitinase protein 40/Soluble interleukin-2 receptor/Copeptin分类
医药卫生引用本文复制引用
季鹏,张云..支气管镜肺泡灌洗辅助治疗对重症肺炎患儿血清YKL-40、sIL-2R、Copeptin水平的影响[J].生命科学仪器,2024,22(4):73-75,3.
