石油化工2024，Vol.53Issue(8)：1098-1103,6.DOI:10.3969/j.issn.1000-8144.2024.08.004
创面组织再生修复材料的安全性和有效性评价技术研究进展
Progress of safety and effectiveness evaluation technology of materials for wound tissue regeneration and repair
摘要
Abstract
Newly developed biomedical materials for tissue regeneration and repair can promote cell proliferation and immigration in wounds,accelerate wound healing,and enhance healing quality.With the development of these new materials,the traditional evaluation method and technology are no longer completely applicable.Therefore,the recent progress of research on characterization,biosafety,and effectiveness evaluation of newly developed materials for wound tissue regeneration and repair was summarized.The chemical property,degradation and absorption,physical property,and biocompatibility evaluation requirement of the materials were introduced,and the established effectiveness evaluation technology was described,including in vitro cell proliferation,cell immigration,in vitro barrier protection,and microangiogenesis tests,as well as in vivo animal wound modeling and wound healing effectiveness evaluation method.关键词
再生材料/创面修复/安全性/有效性/评价Key words
material for tissue regeneration/wound repair/safety/effectiveness/evaluation分类
自科综合引用本文复制引用
王春仁,戴建英,佟微,俞铁锋..创面组织再生修复材料的安全性和有效性评价技术研究进展[J].石油化工,2024,53(8):1098-1103,6.基金项目
国家重点研发计划揭榜挂帅项目(2022YFC2401802) （2022YFC2401802）
浙江省科技计划项目(2021C03115) （2021C03115）
杭州市科技发展计划项目(202004A24). （202004A24）
