危重创伤患者输血治疗后血小板、纤维蛋白原与输血不良反应的相关性研究OA

Objective To explore the correlations of platelet and fibrinogen with adverse reactions of blood transfusion in critically ill trauma patients after blood transfusion therapy.Methods 84 patients with critically ill trauma were treated with blood transfusion.The levels of platelets and fibrinogen before and after blood transfusion were compared,and the correlations of platelet and fibrinogen with the adverse reactions were analyzed.Results The levels of platelet and fibrinogen increased gradually at 24～72 h after blood transfusion.After blood transfusion,the platelet and fibrinogen levels in the occurrence group were lower than those in the non-occurrence group(P<0.05),and the platelet and fibrinogen levels were negatively correlated with the occurrence of adverse reactions(r<0,P<0.05).Conclusions The platelet and fibrinogen of critically ill trauma patients after blood transfusion therapy are closely related to the risk of adverse reactions.