血清胆红素与尿酸检测对冠心病患者临床检验的价值研究OA

Objective To study the clinical test value of serum bilirubin(BIL)and uric acid(UA)in patients with coronary heart disease(CHD).Methods A total of 60 patients with CHD diagnosed in Ningdu County Hospital of Traditional Chinese Medicine from January 2021 to March 2023 were selected as the study subjects and set as CHD group.Another 60 healthy people who underwent physical examination during the same period were selected as healthy group.Serum BIL and UA were detected in both groups.Serum BIL[total bilirubin(TBIL),direct bilirubin(DBIL),indirect bilirubin(IBIL)]and UA test results were compared between CHD group and healthy group.Serum BIL and UA levels in patients with different coronary stenosis grades and different types of CHD were analyzed.Taking the results of coronary angiography as the gold standard,the diagnostic efficacy of serum BIL,UA alone and combined detection on CHD was analyzed.Results The levels of serum TBIL,DBIL and IBIL in CHD group were lower than those in healthy group,and the level of UA was higher than that in healthy group(P＜0.05).The levels of BIL,DBIL and IBIL from high to low were grade Ⅰ＞grade Ⅱ＞grade Ⅲ＞grade Ⅳ,and the levels of UA from high to low were grade Ⅳ＞grade Ⅲ＞grade Ⅱ＞grade Ⅰ(P＜0.05).The levels of TBIL,DBIL and IBIL from high to low were stable angina pectoris(SAP)＞unstable angina pectoris(UAP)＞acute myocardial infarction(AMI),and the levels of UA from high to low were AMI＞UAP＞SAP(P＜0.05).The sensitivity,accuracy and specificity of combined detection of serum BIL and UA in the diagnosis of CHD were higher than those of single detection(P＜0.05).Conclusion The detection of serum BIL and UA has a good screening and differential effect on CHD disease,and the combined detection of the two has higher diagnostic efficiency.