医学新知2024，Vol.34Issue(8)：936-942,7.DOI:10.12173/j.issn.1004-5511.202406092
CD24在肿瘤微环境中的作用及治疗研究进展
Research progress on the role and treatment of CD24 in the tumor microenvironment
摘要
Abstract
Cluster of differentiation 24(CD24)is a surface protein anchored by mucin-like phosphatidylinositol.It is highly expressed in most malignant tumors,promotes tumor occurrence and progression through various mechanisms,and plays an important role in the tumor microenvironment.CD24 has shown promising prospects for anti-tumor therapy in both in vitro and in vivo experiments.This article reviewed the role of CD24 in the tumor microenvironment in the proliferation,invasion and metastasis of malignant tumors,and describes the related therapeutic strategies of CD24-targeting monoclonal antibodies,antibody-drug conjugates,chimeric antigen receptor,and nanoparticle-mediated drug delivery,to provide reference for CD24-targeted therapy.关键词
CD24/肿瘤微环境/恶性肿瘤Key words
CD24/Tumor microenvironment/Malignant tumors引用本文复制引用
于欣静,乔晓娟..CD24在肿瘤微环境中的作用及治疗研究进展[J].医学新知,2024,34(8):936-942,7.基金项目
内蒙古自治区自然科学基金项目(2021MS08153) （2021MS08153）
内蒙古自治区高校青年科技英才项目(NJYT22011) （NJYT22011）
内蒙古自治区高等学校科学研究项目(NJZY21596) （NJZY21596）
内蒙古自治区卫生健康科技计划项目(202201295) （202201295）
内蒙古医科大学科技百万工程项目[YKD2020KJBW(LH)039] （LH）
内蒙古医科大学"致远"人才计划善学人才项目(ZY0202022) （ZY0202022）
