湖北医药学院学报2024，Vol.43Issue(4)：385-389,5.DOI:10.13819/j.issn.2096-708X.2024.04.009
基于质谱成像分析黄芩切片主要代谢产物空间分布
Spatial Distribution of the Main Metabolites in Radix Scutellariae Slices Based on Mass Spectrometry Imaging
摘要
Abstract
Objective To investigate the spatial distribution of the main metabolites in Radix Scutellariae slices.Methods An atmospheric pressure mass spectrometry imaging was constructed based on laser desorption ionization,to analyze the the main metabolites in Radix Scutellariae slices.Results Anthraquinone products had similar distribution,with the majority being concentrated in the root epidermis and some in the edge of the vascular column.Additionally,baicalin,the main ac-tive ingredient of Radix Scutellariae,was found to be distributed throughout the entire section.Conclusion This study dem-onstrates that mass spectrometry imaging can be used to analyze the spatial distribution of endogenous molecules in Chinese medicine slices,which provides a new research tool for the cultivation and processing of these medicines.关键词
黄芩/代谢产物/质谱成像Key words
Radix Scutellariae/Metabolites/Mass spectrometry imaging引用本文复制引用
肖雪,关孝康,徐周毅,陆桥..基于质谱成像分析黄芩切片主要代谢产物空间分布[J].湖北医药学院学报,2024,43(4):385-389,5.基金项目
国家自然科学基金青年项目(22304050) （22304050）
湖北省自然科学基金青年项目(2023AFB271) （2023AFB271）
湖北医药学院人才启动基金计划项目(2022QDJZR007) （2022QDJZR007）
武当特色中药研究湖北省重点实验室(湖北医药学院)开放课题(WDCM2023021) （湖北医药学院）
