中国病理生理杂志2024，Vol.40Issue(8)：1529-1535,7.DOI:10.3969/j.issn.1000-4718.2024.00.020
PI3K/Akt相关信号通路在神经细胞病理生理机制中的研究进展
Progress in role of PI3K/Akt-related signaling pathways in pathophysio-logical mechanism of neural cells
摘要
Abstract
The phosphatidylinositol 3-kinase(PI3K)/protein kinase B(PKB/Akt)signaling pathway plays an important role in various biological processes,including cell growth,proliferation,differentiation,and apoptosis.The PI3K/Akt-related signaling pathways have been extensively studied,and they regulate neural cells to exert different or simi-lar functions.This study reviews the research progress on PI3K/Akt-related signaling pathways in apoptosis,autophagy,oxidative stress,neuroinflammation,and other pathophysiological mechanisms in neural cells.关键词
PI3K/Akt信号通路/神经细胞/细胞凋亡/自噬/氧化应激Key words
PI3K/Akt signaling pathway/neural cells/apoptosis/autophagy/oxidative stress分类
医药卫生引用本文复制引用
曾广红,朱彤,邹磊,周杰..PI3K/Akt相关信号通路在神经细胞病理生理机制中的研究进展[J].中国病理生理杂志,2024,40(8):1529-1535,7.基金项目
甘肃省卫生行业科研计划项目(No.GSWSKY2018-43) （No.GSWSKY2018-43）
中国人民解放军联勤保障部队第九四〇医院研究生课题(No.2022yxky011) （No.2022yxky011）
甘肃省科技计划项目(No.23JRRA532) （No.23JRRA532）
