中国当代儿科杂志2024，Vol.26Issue(9)：989-994,6.DOI:10.7499/j.issn.1008-8830.2404130
代谢组学在儿童肠易激综合征诊治中的研究进展
Research progress of metabolomics in children with irritable bowel syndrome
摘要
Abstract
Irritable bowel syndrome(IBS)is a common functional gastrointestinal disorder characterized by symptoms such as abdominal pain,diarrhea,constipation,and indigestion.Given its unclear etiology and pathogenesis,and the absence of specific biomarkers,clinical diagnosis and treatment of IBS continue to pose significant challenges.In recent years,metabolomics technology,known for its non-invasive,high-throughput,high-precision,and highly reproducible features,has been widely applied in the diagnosis,treatment,and prognosis of various diseases.Therefore,metabolomics technology is expected to offer novel insights and methodologies for the biological mechanism research,diagnosis,and treatment of IBS.This article reviews recent advancements in the application of metabolomics to IBS,exploring its potential value in the clinical diagnosis and treatment of children with this condition.关键词
肠易激综合征/代谢组学/生物标志物/代谢通路/儿童Key words
Irritable bowel syndrome/Metabolomics/Biomarker/Metabolic pathway/Child引用本文复制引用
陈小龙,江米足..代谢组学在儿童肠易激综合征诊治中的研究进展[J].中国当代儿科杂志,2024,26(9):989-994,6.基金项目
"十四五"国家重点研发计划项目(2023YFC2706500)及课题(2023YFC2706504) （2023YFC2706500）
国家中心自主立项项目(G20A0008). （G20A0008）
