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结核病短程治疗研究:回顾与展望

李杨 孙峰 张文宏

中国防痨杂志2024,Vol.46Issue(9):991-997,7.
中国防痨杂志2024,Vol.46Issue(9):991-997,7.DOI:10.19982/j.issn.1000-6621.20240219

结核病短程治疗研究:回顾与展望

Short-course treatment for tuberculosis:past achievements and future directions

李杨 1孙峰 1张文宏1

作者信息

  • 1. 国家传染病医学中心/复旦大学附属华山医院,上海 200040||上海市传染病与生物安全应急响应重点实验室/上海市感染与免疫科技创新中心,上海 200040
  • 折叠

摘要

Abstract

The global decline in tuberculosis(TB)incidence has been disappointingly slow,significantly lagging behind the milestones set by the World Health Organization's End TB Strategy.Consequently,the development and implementation of effective short-course treatment regimens have become imperative.This review aims to examine the progress of short-course TB treatments over the past few decades and evaluate the efficacy of current therapeutic approaches,providing essential references and support for optimizing future treatment strategies.Through a systematic review of the literature and the latest clinical trial data,we analyzed the efficacy,safety,and application scenarios of various short-course treatment regimens.Furthermore,we summarized the main strategies for current short-course treatments.Despite existing challenges,significant progress in tuberculosis short-course treatment is anticipated in the coming years,driven by the development of novel drugs,dose optimization,and more precise patient evaluation.

关键词

结核/临床方案/治疗应用/总结性报告(主题)

Key words

Tuberculosis/Clinical protocols/Therapeutic uses/Consensus reports

分类

医药卫生

引用本文复制引用

李杨,孙峰,张文宏..结核病短程治疗研究:回顾与展望[J].中国防痨杂志,2024,46(9):991-997,7.

基金项目

Clinical Research Plan of SHDC(SHDC2020CR1011B) (SHDC2020CR1011B)

The Three-year(2020-2022)Action Plan Project for Public Health from Shanghai Municipal Health Commission(GWV-3.1) (2020-2022)

National Natural Science Foundation of China(82102406) (82102406)

RCT Duplicate program of SHDC(SHDC2024CRI047) (SHDC2024CRI047)

Shanghai Municipal Science and Technology Major Project(HS2021SHZX001) 上海申康医院发展中心临床三年行动计划资助(SHDC2020CR1011B) (HS2021SHZX001)

上海市加强公共卫生体系建设三年行动计划(2020-2022年)(GWV-3.1) (2020-2022年)

国家自然科学基金青年基金(82102406) (82102406)

上海申康医院发展中心模拟RCT 项目(SHDC2024CRI047) (SHDC2024CRI047)

上海市科技重大专项(HS2021SHZX001) (HS2021SHZX001)

中国防痨杂志

OA北大核心CSTPCD

1000-6621

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