中国防痨杂志2024,Vol.46Issue(9):991-997,7.DOI:10.19982/j.issn.1000-6621.20240219
结核病短程治疗研究:回顾与展望
Short-course treatment for tuberculosis:past achievements and future directions
摘要
Abstract
The global decline in tuberculosis(TB)incidence has been disappointingly slow,significantly lagging behind the milestones set by the World Health Organization's End TB Strategy.Consequently,the development and implementation of effective short-course treatment regimens have become imperative.This review aims to examine the progress of short-course TB treatments over the past few decades and evaluate the efficacy of current therapeutic approaches,providing essential references and support for optimizing future treatment strategies.Through a systematic review of the literature and the latest clinical trial data,we analyzed the efficacy,safety,and application scenarios of various short-course treatment regimens.Furthermore,we summarized the main strategies for current short-course treatments.Despite existing challenges,significant progress in tuberculosis short-course treatment is anticipated in the coming years,driven by the development of novel drugs,dose optimization,and more precise patient evaluation.关键词
结核/临床方案/治疗应用/总结性报告(主题)Key words
Tuberculosis/Clinical protocols/Therapeutic uses/Consensus reports分类
医药卫生引用本文复制引用
李杨,孙峰,张文宏..结核病短程治疗研究:回顾与展望[J].中国防痨杂志,2024,46(9):991-997,7.基金项目
Clinical Research Plan of SHDC(SHDC2020CR1011B) (SHDC2020CR1011B)
The Three-year(2020-2022)Action Plan Project for Public Health from Shanghai Municipal Health Commission(GWV-3.1) (2020-2022)
National Natural Science Foundation of China(82102406) (82102406)
RCT Duplicate program of SHDC(SHDC2024CRI047) (SHDC2024CRI047)
Shanghai Municipal Science and Technology Major Project(HS2021SHZX001) 上海申康医院发展中心临床三年行动计划资助(SHDC2020CR1011B) (HS2021SHZX001)
上海市加强公共卫生体系建设三年行动计划(2020-2022年)(GWV-3.1) (2020-2022年)
国家自然科学基金青年基金(82102406) (82102406)
上海申康医院发展中心模拟RCT 项目(SHDC2024CRI047) (SHDC2024CRI047)
上海市科技重大专项(HS2021SHZX001) (HS2021SHZX001)