高清智能电子染色内镜联合频闪喉镜在声带白斑患者中的应用效果OACSTPCD

Objective To analyze the application effect of high-definition intelligent electronic staining endoscopy(i-Scan)combined with stroboscope in patients with vocal cord leukoplakia.Methods A retrospective study was carried out on 80 patients with vocal cord leukoplakia from January 2021 to December 2022.All the patients were confirmed by CO2 laser laryngoscopy to determine their pathological properties,and all the patients were given i-Scan and stroboscope before operation.Analyze the pathological diagnosis of vocal cord lesions by i-Scan and stroboscope,compare the lesion vascular morphology score and lesion boundary score of i-Scan and stroboscope,observe the microvascular morphological characteristics and pathological type distribution under i-Scan in patients with vocal cord leukoplakia,as well as the mucosal wave characteristics and pathological type distribution under stroboscope in patients with vocal cord leukoplakia,and analyze the predictive value of i-Scan and stroboscope on microvascular morphology and mucosal wave changes by receiver operator characteristic curve(ROC curve).Results Taking the postoperative pathology as the final diagnosis,5 patients with vocal cord leukoplakia failed to be examined by i-Scan and stroboscope because of the white spot or necrotic substance on the surface.The diagnostic accuracy rate of i-Scan was 68.00%(51/75),and the diagnostic accuracy rate of stroboscope was 89.33%(67/75).The lesion vascular morphology score and lesion boundary score of i-Scan were higher than those of stroboscope(P<0.05).67 cases had horizontal vascular changes,mainly with simple hyperplasia of squamous epithelium,chronic inflammation and mild dysplasia,and 8 cases had vertical vascular changes,mainly with mild dysplasia.The change of microvessel morphology and direction under i-Scan was significantly different from the pathological results(P<0.05),and was positively correlated.62 cases had normal and mild mucosal wave attenuation,mainly with simple hyperplasia of squamous epithelium,chronic inflammation and mild dysplasia,13 cases had severe attenuation and disappearance,mainly with simple hyperplasia of squamous epithelium.The degree of mucosal wave attenuation under stroboscope was statistically significant(P<0.05),and was positively correlated with the benign and malignant results.There was no statistically significant difference in the predictive effect of i-Scan or stroboscope alone on the benign and malignant of patients with vocal cord leukoplakia(P>0.05),while the predictive effect of i-Scan combined with stroboscope was better than that of alone(P<0.05).Conclusion i-Scan combined with stroboscope has a better value in evaluating the submucosal microvessels,mucosal waves and morphology of vocal cords in patients with vocal cord leukoplakia,and the combined application has a better predictive value for benign and malignant lesions than the single application.