中国兽医科学2024，Vol.54Issue(9)：1253-1258,6.DOI:10.16656/j.issn.1673-4696.2024.0158
机械力转导在抗病毒免疫反应中的作用
Mechanotransduction in antiviral immune response
摘要
Abstract
Cells are subjected to mechanical forces throughout their life cycle.This process is mediated by molecules such as LINC,Lamin A/C,TRPV4,and integrins.Recent studies have shown that mechano-transduction plays a crucial role in the development of the immune system and immune responses.After infection with pathogens,mechanotransduction regulates the activation of cellular immune responses,cytokine production,metabolism,proliferation,and transport.This review provides an in-depth analysis of the effects of mechanotransduction on the immune response,the inflammatory response,and the regula-tion of immune cell function.关键词
LINC/Lamin A/C/Piezo 1/TRPV4/免疫应答Key words
LINC/Lamin A/C/Piezol/TRPV4/immune response分类
农业科技引用本文复制引用
王常英,张涛清,郑海学,伍国强,秦晓东..机械力转导在抗病毒免疫反应中的作用[J].中国兽医科学,2024,54(9):1253-1258,6.基金项目
国家重点研发计划项目(2021YFD1800300) （2021YFD1800300）
甘肃省重大专项(22ZD6NA001) （22ZD6NA001）
中国农业科学院创新计划项目(CAAS-CSLPDCP-2023002) （CAAS-CSLPDCP-2023002）
2024创新工程项目(CAAS-ASTIP-2021-LVRI) （CAAS-ASTIP-2021-LVRI）
