中国实用内科杂志2024，Vol.44Issue(7)：547-552,6.DOI:10.19538/j.nk2024070105
慢性胰腺炎干细胞治疗研究进展
Advances in stem cell therapy in chronic pancreatitis
摘要
Abstract
Chronic pancreatitis(CP)has a complex pathogenesis and still lacks a targeted and effective treatment.Stem cells have the ability to regulate inflammation and immune response,and promote repair and regeneration of damaged tissues,which have been applied in many organs or tissues.ln recent years,stem cell therapy has received increasing attention in CP,and studies have demonstrated its role in anti-inflammation and anti-fibrosis.However,there is still a lack of research on the treatment of painful symptoms of CP and complications such as diabetes mellitus and pancreatic exocrine insufficiency.Currently,stem cell research in CP is only at the cellular and animal level,and no clinical trials have yet been performed.This paper summarizes the research progress of stem cell therapy in CP in pancreatic inflammation and fibrosis,abdominal pain,pancreatic exocrine insufficiency,and diabetes mellitus.关键词
慢性胰腺炎/干细胞治疗/糖尿病/间充质干细胞Key words
chronic pancreatitis/stem cell therapy/diabetes mellitus/mesenchymal stem cells分类
医药卫生引用本文复制引用
周筱雨,胡良皞,李兆申..慢性胰腺炎干细胞治疗研究进展[J].中国实用内科杂志,2024,44(7):547-552,6.基金项目
国家自然科学基金(82070664,82270679) （82070664,82270679）
上海市曙光计划(20SG36) （20SG36）
上海申康医院发展中心新兴前沿项目(SHDC12021107) （SHDC12021107）
