中国实用内科杂志2024，Vol.44Issue(8)：625-629,5.DOI:10.19538/j.nk2024080103
高血压基础研究进展
Advances in basic research on hypertension
李晨 1宋雷2
作者信息
- 1. 国家心血管病中心中国医学科学院阜外医院,心肌病病区,北京 100037
- 2. 国家心血管病中心中国医学科学院阜外医院,心肌病病区,北京 100037||国家心血管病中心中国医学科学院阜外医院,国家心血管病重点实验室,北京 100037||国家心血管病中心中国医学科学院阜外医院,国家心血管疾病临床研究中心,北京 100037
- 折叠
摘要
Abstract
Hypertension is the most common chronic cardiovascular disease worldwide,and one of the leading factors for all-cause death and cardiovascular morbidity.The pathogenesis of hypertension is complex,involving the combined action of genetic,social,and environmental factors.Comprehensive and in-depth basic research on the onset and development mechanisms of hypertension facilitates the precise prevention and early intervention of hypertension.This review summarizes the latest basic research advances in hypertension,focusing on the mechanisms of blood pressure regulation and hypertensive pathogenesis from the facets of genetic susceptibility,epigenetic modification,circadian rhythm regulation,immune modulation,and vascular remodeling,and elaborating the cross-link under the concept of onco-hypertension.This review provides new insights and targets for the prevention and treatment of hypertension.关键词
高血压/发病机制/基础研究Key words
hypertension/pathogenesis/fundamental research分类
医药卫生引用本文复制引用
李晨,宋雷..高血压基础研究进展[J].中国实用内科杂志,2024,44(8):625-629,5.
