中国现代医学杂志2024，Vol.34Issue(16)：94-98,5.DOI:10.3969/j.issn.1005-8982.2024.16.016
合成磁共振序列在轻度膝骨性关节炎磁共振扫描图像质量评价及弛豫定量中的应用
Application of synthetic MRI in evaluation of image quality and quantitative relaxometry in MRI scans of mild knee osteoarthritis
摘要
Abstract
Objective To explore the application value of the synthetic magnetic resonance imaging(MRI)method termed MAGnetic resonance image Compilation(MAGiC)in evaluation of image quality and quantitative relaxometry in MRI scans of mild knee osteoarthritis(KOA).Methods A total of 80 knee MRI images were collected from 20 normal volunteers and 20 patients with mild KOA in our hospital from March 2023 to March 2024.The MRI scanning sequences included conventional sequences T1 WI,T2WI,PDWI,PDWI-FS,and MAGiC sequences.The MAGiC images were imported into post-processing software to obtain decomposed T1WI,T2WI,PDWI,and PDWI-STIR images,and T2,T1,and PD quantitative maps.The image quality of conventional sequences and MAGiC decomposed sequences and the detection rate of cartilage injury in the two groups of images were compared.Meanwhile,the T1,T2,and PD values of the cartilage in the normal control group and the mild KOA group were measured on the quantitative maps of the MAGiC sequences.Results The image quality of conventional sequences T1WI,T2WI,PDWI,and fat-suppressed PDWI(PDWI-FS and PDWI-STIR)was higher than that of MAGiC decomposed sequences(P＜0.05).There was no difference in the detection rate of cartilage injury in mild KOA patients between the conventional sequences and the MAGiC decomposed sequences(P＞0.05).The T1,T2,and PD relaxation time of the normal control group were higher than those in the mild KOA group(P＜0.05).Conclusions The images decomposed from MAGiC sequences can effectively detect cartilage injury in patients with mild KOA,and the multiparameter quantification of relaxation helps to quantify the degree of cartilage injury among these patients.Thus,MAGiC is of high clinical application value for diagnosis and monitoring disease progression of early-stage KOA.关键词
膝骨性关节炎/合成磁共振序列,磁共振成像/弛豫定量Key words
knee osteoarthritis/synthetic magnetic resonance imaging sequences/magnetic resonance imaging/quantitative relaxometry分类
医药卫生引用本文复制引用
卢镱,孟莉,吴鑫鑫,龚远金,聂吉林..合成磁共振序列在轻度膝骨性关节炎磁共振扫描图像质量评价及弛豫定量中的应用[J].中国现代医学杂志,2024,34(16):94-98,5.基金项目
湖南省自然科学基金(No:2023JJ30927) （No:2023JJ30927）
