中国药科大学学报2024，Vol.55Issue(4)：443-453,11.DOI:10.11665/j.issn.1000-5048.2024051301
鼠李科植物枣多糖的活性机制及其结构特征研究进展
Research progress on active mechanism and structure feature of polysaccharides from Zizyphus jujube in Rhamnaceae plants
摘要
Abstract
The genus jujube(Ziziphus jujuba Mill.)within the Rhamnaceae family encompasses numerous varieties,such as Ziziphus jujuba Mill.var.jujuba,Ziziphus jujuba var.inermis,and var.spinosa,etc.Among these,the jujube fructus has the most abundant cultivated variants across the country,including Ziziphus jujuba cv.Hamidazao and Ziziphus jujuba cv.Huanghetanzao.Jujube plants are rich in variety and are used for both medicinal and food purposes.Polysaccharides,one of the main active ingredients of jujube,are important medicinal components that contribute to its efficacy.Jujube polysaccharides have been found to promote hematopoiesis,exhibit antioxidant and anti-tumor activities,repair liver damage,regulate the immune system,and provide anti-inflammatory effects.By comprehensively summarizing and analyzing the literature on jujube polysaccharides from different varieties and origins,this paper reviews the potential mechanisms of action of jujube polysaccharides in exerting biological activities.It also summarizes the primary structural features,such as relative molecular mass,monosaccharide composition,glycosidic linkage,and the substituent modifications of jujube polysaccharides by sulfation,phosphorylation,carboxymethylation,selenization,and acetylation.This review aims to provide a reference for the research and development of jujube in the fields of innovative polysaccharide drugs and functional foods.关键词
枣多糖/生物活性机制/结构分析/结构改造Key words
jujube polysaccharide/bioactive mechanism/structural analysis/structural modification分类
轻工纺织引用本文复制引用
董小强,文畅,许金丹,史乐雪,胡玉龙,李杰明,董春红,丁侃..鼠李科植物枣多糖的活性机制及其结构特征研究进展[J].中国药科大学学报,2024,55(4):443-453,11.基金项目
河南省自然科学基金项目(No.232300421374) （No.232300421374）
中国博士后科学基金项目(No.2021M690936) This study was supported by the Natural Science Foundation of Henan Province(No.232300421374) （No.2021M690936）
and China Postdoctoral Science Foundation(No.2021M690936) （No.2021M690936）
