中国药房2024，Vol.35Issue(17)：2158-2164,7.DOI:10.6039/j.issn.1001-0408.2024.17.18
中药通过调控细胞自噬治疗支气管哮喘的研究进展
Progress on traditional Chinese medicine in the treatment of bronchial asthma by regulating autophagy
摘要
Abstract
Bronchial asthma(referred to as"asthma")is a heterogeneous airway disease characterized by chronic airway inflammation and airway remodeling.Its pathogenesis is complex,the incidence is high and the disease is easy to repeat.Autophagy plays an important regulatory role in improving asthma symptoms.By regulating autophagy-related proteins and signaling pathways,the active components of traditional Chinese medicine(such as flavonoids,anthraquinones,terpenoids)and traditional Chinese medicine compounds(such as Wuhu decoction,Pingchuan granule,Sanzi yangqin decoction)can inhibit airway inflammatory response,reduce airway hyperresponsiveness,and alleviate airway remodeling,thus playing a role in the treatment of asthma.However,most of the current studies are basic studies,and the quality of evidence is not high.In the future,high-quality clinical and basic studies should be further carried out to fully demonstrate the scientific nature of traditional Chinese medicine in the treatment of asthma by regulating autophagy.关键词
支气管哮喘/自噬/中药活性成分/中药复方/研究进展Key words
bronchial asthma/autophagy/active components of traditional Chinese medicine/traditional Chinese medicine compound/research progress分类
医药卫生引用本文复制引用
李梦茵,宋桂华,王婷婷,任明月..中药通过调控细胞自噬治疗支气管哮喘的研究进展[J].中国药房,2024,35(17):2158-2164,7.基金项目
国家自然科学基金项目(No.82274578) （No.82274578）
河南省中医药学科领军人才培养项目(No.豫卫中医函[2021]8号) （No.豫卫中医函[2021]8号）
河南省"双一流"创建学科中医学科学研究专项(No.HSRP-DFCTCM-2023-3-05) （No.HSRP-DFCTCM-2023-3-05）
