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肺纤维化脂质代谢研究概况

王靖颖 徐泳 许伟辰 谢彤 时晨 单进军

中国药理学通报2024,Vol.40Issue(9):1612-1616,5.
中国药理学通报2024,Vol.40Issue(9):1612-1616,5.DOI:10.12360/CPB202305012

肺纤维化脂质代谢研究概况

Overview of lipid metabolism in pulmonary fibrosis

王靖颖 1徐泳 2许伟辰 1谢彤 1时晨 1单进军1

作者信息

  • 1. 南京中医药大学儿童健康与中医药江苏省高校重点实验室,江苏南京 210023||南京中医药大学医学代谢组学中心,江苏南京 210023
  • 2. 南京中医药大学儿童健康与中医药江苏省高校重点实验室,江苏南京 210023||南京中医药大学中西医结合学院,江苏南京 210023
  • 折叠

摘要

Abstract

Pulmonary fibrosis is a diffuse interstitial lung disease with poor prognosis,and its pathogenesis has not been fully clar-ified.Lipid,as a key component of cell structure involved in signal transduction,plays an important role in maintaining lung function.More and more studies show that lipid changes are closely related to the progress of pulmonary fibrosis.This paper briefly reviews the pulmonary fibrosis disease,the research pro-gress of lipidomics in pulmonary fibrosis and the role of various lipids in pulmonary fibrosis.

关键词

肺纤维化/脂质代谢/脂质组学/甘油磷脂/特发性肺纤维化/脂肪酸

Key words

pulmonary fibrosis/lipid metabolism/lipidomics/glycerol phospholipid/idiopathic pulmonary fibrosis/fatty acid

分类

医药卫生

引用本文复制引用

王靖颖,徐泳,许伟辰,谢彤,时晨,单进军..肺纤维化脂质代谢研究概况[J].中国药理学通报,2024,40(9):1612-1616,5.

基金项目

国家自然科学基金资助项目(No 82174098,81774156) (No 82174098,81774156)

中国药理学通报

OA北大核心CSTPCD

1001-1978

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