中国药理学与毒理学杂志2024，Vol.38Issue(8)：610-618,9.DOI:10.3867/j.issn.1000-3002.2024.08.006
新型冠状病毒感染与宿主糖酵解相互作用研究进展
Research progress in interactions between SARS-CoV-2 infection and host glycolysis
摘要
Abstract
The relationship between glycolysis and viral infectious diseases is close,and the inter-action between viral and host glycolysis is a common mechanism found in a wide range of viruses.Therefore,the regulation of glycolysis may be an important antiviral strategy.The coronavirus diseases 2019 pandemic has brought about a tremendous disaster to humanity,compelling us to seek effective solutions from various perspectives.Severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)infection can induce an increase in host glycolysis,the level of which plays an important role in virus replication and infection,associated with the progression of the disease and a variety of clinical symp-toms and complications.The study on the interaction between host glycolysis and SARS-CoV-2 infec-tion can shed light on the pathogenic mechanism of SARS-CoV-2 and promote the research on related drugs.This article reviews the interactions between SARS-CoV-2 infection and host glycolysis in the hopes of providing a new perspective to understand the relationships between viral infections and disease in terms of metabolic regulation and formulate countermeasures.关键词
新型冠状病毒/感染/糖酵解/相互作用Key words
severe acute respiratory syndrome coronavirus 2/infection/glycolysis/interaction分类
医药卫生引用本文复制引用
李月含,韩露,周文霞..新型冠状病毒感染与宿主糖酵解相互作用研究进展[J].中国药理学与毒理学杂志,2024,38(8):610-618,9.基金项目
国家自然科学基金(82141218) （82141218）
中国科学技术协会青年人才托举工程(2022QNRC001) National Natural Science Foundation of China(82141218) （2022QNRC001）
and China Association for Science and Technology Youth Talent Lift Project(2022QNRC001) （2022QNRC001）
