腹腔镜肝切除术中半肝血流阻断法与间歇性Pringle法对患者术后炎症指标及肝功能的影响OA

Objective:To compare and analyze the effects of hemihepatic vascular control(HVC)and intermittent Pringle maneuver(IPM)on postoperative inflammatory indexes and liver function in laparoscopic hepatectomy.Method:A total of 60 patients who underwent laparoscopic hepatectomy in Weihai Central Hospital from January 2021 to June 2023 were retrospectively analyzed,and they were divided into IPM group(n=32,applied IPM)and HVC group(n=28,applied HVC)according to the hepatic blood flow blocking technique adopted during the operation.Intraoperative bleeding volume,operation time,total hospital stay,inflammatory indexes[white blood cell count(WBC),C reactive protein(CRP)]and liver function indexes[alanine aminotransferase(ALT),aspartate aminotransferase(AST)]were compared between the two groups.Result:There were no significant differences in operation time,intraoperative bleeding volume and CRP level 1 day after operation between the two groups(P>0.05).The total hospital stay of HVC group was shorter than that of control group,and the levels of WBC 1,2 and 5 days after operation were lower than those of IPM group,the levels of CRP 2 and 5 days after operation were lower than those of IPM group,the levels of ALT and AST on the day after operation and 1 and 2 days after operation were significantly lower than those of IPM group,the differences were statistically significant(P<0.05).Conclusion:In laparoscopic hepatectomy,HVC and IPM have no obvious effect on the intraoperative bleeding volume and operation time,but HVC can reduce the postoperative inflammatory reaction and liver function damage,shorten the hospital stay and facilitate the postoperative recovery of patients.