中国医学科学院学报2024，Vol.46Issue(4)：603-609,7.DOI:10.3881/j.issn.1000-503X.15803
补体受体免疫球蛋白超家族分子在调节肝脏免疫反应中的研究进展
Research Progress in Complement Receptor of the Immunoglobulin Superfamily in Regulating Liver Immunity
摘要
Abstract
Kupffer cells(KC),an important subset of immune cells in the liver,are essential for maintaining tissue homeostasis and responding quickly to liver damage.The complement receptor of the immuno-globulin superfamily(CRIg)is a receptor protein on the KC membrane.CRIg can not only capture pathogens in the blood flowing through the liver by complement binding but also mediate immune responses by regulating im-mune cells in the liver.Recent studies have confirmed the role of CRIg in regulating liver immunity.This article reviews the main modes of action of CRIg and the research progress of CRIg in regulating liver immunity.关键词
补体受体免疫球蛋白超家族分子/库普弗细胞/肝脏免疫/病原体Key words
complement receptor of the immunoglobulin superfamily/Kupffer cells/liver immunity/pathogen分类
医药卫生引用本文复制引用
杨树森,李京涛,闫曙光,焦俊喆..补体受体免疫球蛋白超家族分子在调节肝脏免疫反应中的研究进展[J].中国医学科学院学报,2024,46(4):603-609,7.基金项目
国家自然科学基金(82174330) （82174330）
