南京社区老年体检人群主要慢性代谢病变化趋势研究OA北大核心CSTPCD

Objective To analyze the change trend of major chronic metabolic diseases in the older medical examination population in Nanjing community,and to provide reference for the prevention and control strategies of chronic metabolic diseases in the community older population.Methods Based on the national basic public health service program-health management for the older adults,two districts in Nanjing were randomly selected,with both district covering all streets and each street covering all neighborhood/village committees.From 2018-2021,the health checkups for the population aged 65 years and above were continuously tracked and the data were collected through questionnaires,body measurements,and laboratory tests.Generalized estimating equation(GEE)model was used to analyze the change trend of major chronic metabolic diseases among older population in the community.Results Finally 19 314 older adults were included in the study,including 8 222(42.57％)males and 11 092(57.43％)females.GEE analysis showed that the prevalence of diabetes,dyslipidemia,non-alcoholic fatty liver disease,and chronic kidney disease in the older population showed an increasing trend,and the differences were statistically significant(all P＜0.01).The prevalence of overweight,obesity,and hypertension in 2019 were 1.035(95％CI:1.010-1.061),1.105(95％CI:1.076-1.135),and 1.187 times(95％CI:1.148-1.226)of that in 2018,respectively.And the prevalence of overweight,obesity,and hypertension in 2021 were 1.038(95％CI:1.010-1.067),1.205(95％CI:1.170-1.241),and 1.308 times(95％CI:1.264-1.354)of that in 2018.Conclusions The prevalence of major chronic metabolic diseases such as diabetes,dyslipidemia,non-alcoholic fatty liver disease and chronic kidney disease in the older population in Nanjing showes an overall upward trend.The prevention and control situation of chronic metabolic diseases in Nanjing is relatively severe,and primary prevention strategies should be developed and optimized in a timely manner.