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抗免疫球蛋白E药物在儿童哮喘中的合理应用OA

Rational Use of Anti-Immunoglobulin E Drugs for Childhood Asthma

中文摘要英文摘要

儿童哮喘作为一种常见的慢性呼吸道疾病,对患儿的生活质量及家庭负担造成了严重影响.近年来,抗免疫球蛋白E(IgE)药物作为治疗儿童哮喘的新型生物制剂,其疗效和安全性得到了广泛关注.本文综述了抗IgE药物在儿童哮喘治疗中的研究进展,包括作用机制、药物特性、临床应用及与其他治疗药物的联合应用等,旨在探讨抗IgE药物在儿童哮喘中的合理应用策略及治疗展望,以期为临床实践提供参考.

As a common chronic respiratory disease,childhood asthma seriously affects the quality of life and increases family burden.In recent years,anti-immunoglobulin E(IgE)drugs have been used as a novel biologic for the treatment of childhood asthma,and their efficacy and safety have received extensive attention.Here,we reviewed the research progress of anti-IgE drugs in the treatment of childhood asthma,including their mechanism of action,drug characteristics,clinical application and combination use with other drugs,in order to explore the strategy for rational use of anti-IgE drugs in the treatment of childhood asthma and discuss the treament prospects,so as to provide reference for clinical practice.

陈静;向莉

国家儿童医学中心,首都医科大学附属北京儿童医院过敏反应科,北京 100045

临床医学

儿童哮喘治疗生物制剂抗IgE药物合理应用

childhood asthmatreatmentbiologicsanti-IgE drugsrational application

《中国合理用药探索》 2024 (008)

60-64 / 5

北京市首批临床研究联合体儿科研联体试点单位过敏疾病分级诊疗项目;"生机计划2023"(202406170002)

10.3969/j.issn.2096-3327.2024.08.005

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