中国中医药信息杂志2024，Vol.31Issue(9)：18-23,6.DOI:10.19879/j.cnki.1005-5304.202308465
基于络病理论探讨靶向肺血管重塑治疗肺动脉高压
Exploration on Targeted Pulmonary Vascular Remodeling for the Treatment of Pulmonary Hypertension Based on Collateral Disease Theory
摘要
Abstract
Pulmonary hypertension(PH)is a progressive pulmonary vascular disease that can lead to right heart failure and death.In recent years,the incidence of PH has been increasing year by year and there is a lack of effective treatment.TCM can play an important synergistic role in the treatment of PH.Pulmonary vascular remodeling is a core pathological feature of PH,which is closely related to the physiological structure and pathological changes of the collaterals.Based on the collateral disease theory,this article described the key pathogenesis of PH in TCM and Western medicine,including the lesions of the pulmonary and cardiovascular complexes and pulmonary vascular remodeling,analyzed the physiology of the"collateral-vessel"in PH,sorting out the pathological correlation,and explored TCM targeting pulmonary vascular remodeling in the identification and treatment of PH,so as to provide a new way of thinking for the clinical treatment of PH.关键词
肺动脉高压/络病理论/肺血管重塑/理论探讨Key words
pulmonary hypertension/collateral disease theory/pulmonary vascular remodeling/theoretical exploration分类
中医学引用本文复制引用
曹闲雅,谭骏岚,郑润锈,易健,彭果然,丁蓉珍,李霞,王飞英,戴爱国..基于络病理论探讨靶向肺血管重塑治疗肺动脉高压[J].中国中医药信息杂志,2024,31(9):18-23,6.基金项目
国家自然科学基金(82370069、82200066、82305214) （82370069、82200066、82305214）
湖南省自然科学基金(2021JJ30017) （2021JJ30017）
湖南省中医药科研计划重点项目(C2022001) （C2022001）
湖南省研究生科学研究创新项目重点项目(CX20230792) （CX20230792）
湖南中医药大学中西医结合学院-明康中锦联合基金(2022MKZJ02) （2022MKZJ02）
