中国中医药信息杂志2024,Vol.31Issue(9):191-196,6.DOI:10.19879/j.cnki.1005-5304.202309051
中药黄酮治疗帕金森病基础研究进展
Research Progress in TCM Flavonoids for the Treatment of Parkinson Disease
摘要
Abstract
Parkinson disease is a common neurodegenerative disease.At present,the main therapeutic drugs have problems such as adverse reactions,lack of targeting,and low bioavailability.The development of new drugs is an important direction for research related to Parkinson disease.TCM flavonoids have various pharmacological activities and are widely used in anti-tumor and cardiovascular disease treatment,but there is relatively little research on their intervention in neurological diseases.This article elaborated on the mechanism of intervention of TCM flavonoids in Parkinson disease and summarized treatment strategies from six categories:flavonoids,flavonols,isoflavones,flavonoid glycosides,dihydroflavonols,and others,with the purpose to provide reference for the research and clinical application of TCM flavonoids.关键词
帕金森病/中药黄酮/抗氧化/铁代谢/综述Key words
Parkinson disease/TCM flavonoids/antioxidant/iron metabolism/review分类
中医学引用本文复制引用
陈竑瑞,薛晓娟,李雪,解天,陈昳冰..中药黄酮治疗帕金森病基础研究进展[J].中国中医药信息杂志,2024,31(9):191-196,6.基金项目
国家自然基金委专项"医药卫生领域工程科技未来20年发展战略研究"(L2124006) (L2124006)
国家自然科学基金青年科学基金(82104399) (82104399)