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中药黄酮治疗帕金森病基础研究进展

陈竑瑞 薛晓娟 李雪 解天 陈昳冰

中国中医药信息杂志2024,Vol.31Issue(9):191-196,6.
中国中医药信息杂志2024,Vol.31Issue(9):191-196,6.DOI:10.19879/j.cnki.1005-5304.202309051

中药黄酮治疗帕金森病基础研究进展

Research Progress in TCM Flavonoids for the Treatment of Parkinson Disease

陈竑瑞 1薛晓娟 2李雪 2解天 2陈昳冰2

作者信息

  • 1. 天津中医药大学第二附属医院临床药理中心,天津 300150
  • 2. 天津中医药大学中医药研究院组分中药国家重点实验室,天津 301617
  • 折叠

摘要

Abstract

Parkinson disease is a common neurodegenerative disease.At present,the main therapeutic drugs have problems such as adverse reactions,lack of targeting,and low bioavailability.The development of new drugs is an important direction for research related to Parkinson disease.TCM flavonoids have various pharmacological activities and are widely used in anti-tumor and cardiovascular disease treatment,but there is relatively little research on their intervention in neurological diseases.This article elaborated on the mechanism of intervention of TCM flavonoids in Parkinson disease and summarized treatment strategies from six categories:flavonoids,flavonols,isoflavones,flavonoid glycosides,dihydroflavonols,and others,with the purpose to provide reference for the research and clinical application of TCM flavonoids.

关键词

帕金森病/中药黄酮/抗氧化/铁代谢/综述

Key words

Parkinson disease/TCM flavonoids/antioxidant/iron metabolism/review

分类

中医学

引用本文复制引用

陈竑瑞,薛晓娟,李雪,解天,陈昳冰..中药黄酮治疗帕金森病基础研究进展[J].中国中医药信息杂志,2024,31(9):191-196,6.

基金项目

国家自然基金委专项"医药卫生领域工程科技未来20年发展战略研究"(L2124006) (L2124006)

国家自然科学基金青年科学基金(82104399) (82104399)

中国中医药信息杂志

OACSTPCD

1005-5304

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