中国卒中杂志2024，Vol.19Issue(7)：755-761,7.DOI:10.3969/j.issn.1673-5765.2024.07.004
基于ASPECTS分区的烟雾病CT灌注与DSA侧支代偿的相关性研究
A Study on the Correlation between ASPECTS-Based CT Perfusion and DSA Collateral Compensation in Moyamoya Disease
摘要
Abstract
Objective To explore the correlation between CT perfusion and DSA collateral compensation and the risk factors affecting cerebral hemisphere perfusion in patients with Moyamoya disease. Methods A total of 115 adult Moyamoya disease patients with 230 cerebral hemispheres were enrolled in this study,and their DSA and CT perfusion data were collected.The ASPECTS was used to divide the brain regions and score four perfusion hemodynamic indicators including time to peak(TTP),mean transit time(MTT),cerebral blood flow(CBF),and cerebral blood volume(CBV),and to score the cerebrovascular collateral compensation displayed by DSA.Spearman correlation analysis and multiple linear regression analysis were performed on the four perfusion hemodynamic indicators and the DSA collateral compensation score. Results In 115 patients with Moyamoya disease,MTT score(r=0.41,P＜0.01)was positively correlated with the DSA collateral compensation score.The DSA collateral compensation score(β=0.31,P=0.02),gender(β=1.20,P=0.01),clinical type(β=2.94,P＜0.01),and history of stroke(β=-1.19,P=0.02)were independent influencing factors for cerebral perfusion changes.Female patients had better perfusion than male patients(P=0.02),hemorrhagic patients had better perfusion than ischemic patients(P=0.01),and patients without a history of stroke had better perfusion than those with a history of stroke(P=0.03). Conclusions The DSA collateral compensation score was correlated with the MTT score.Moreover,the DSA collateral compensation score,gender,clinical type,and history of stroke were independent influencing factors for cerebral hemisphere perfusion.CT perfusion should be considered when evaluating bypass vessels,neovascularization,and postoperative prognosis.关键词
烟雾病/计算机断层扫描灌注/侧支代偿Key words
Moyamoya disease/Computed tomography perfusion/Collateral compensation分类
临床医学引用本文复制引用
杜海斌,孙剑,刘炜,张东..基于ASPECTS分区的烟雾病CT灌注与DSA侧支代偿的相关性研究[J].中国卒中杂志,2024,19(7):755-761,7.基金项目
国家重点研发计划项目(2021YFC2500502) （2021YFC2500502）
