益气养阴助阳法联合艾灸神阙穴治疗老年慢性心力衰竭患者的临床效果OA
Clinical Effect of Invigorating Qi and Nourishing Yin and Assisting Yang Combined with Moxibustion Shenque Point on Elderly Patients with Chronic Heart Failure
目的:分析益气养阴助阳法联合艾灸神阙穴治疗老年慢性心力衰竭患者的临床效果.方法:选取 2022 年 4 月—2023 年 6 月保定市第一中医院收治的 106 例老年慢性心力衰竭患者,按照随机数表法将其分为两组,对照组 53 例实施常规西药治疗,治疗组 53 例在此基础上采用益气养阴助阳法联合艾灸神阙穴治疗.对比两组疗效、安全性,以及治疗前后的症状积分、炎症因子、心功能相关指标.结果:(1)治疗组治疗总有效率高于对照组,差异有统计学意义(P<0.05);两组不良反应发生率对比,差异无统计学意义(P>0.05).(2)治疗前,两组各项症状积分对比,差异无统计学意义(P>0.05);治疗后,两组各项症状积分均低于治疗前,且与对照组相比,治疗组心悸、胸闷胸痛、气短乏力、下肢水肿症状积分均明显更低,差异有统计学意义(P<0.05).(3)治疗前,两组心功能相关指标对比,差异无统计学意义(P>0.05);治疗后,两组各项心功能相关指标均明显优于治疗前,且与对照组相比,治疗组左心室射血分数(LVEF)明显更高,6 分钟步行距离明显更长,左心室舒张末期内径(LVEDD)、左心室收缩末期内径(LVESD)、氨基末端脑钠肽前体(NT-proBNP)均明显更低,差异有统计学意义(P<0.05).(4)治疗前,两组炎症因子水平对比,差异无统计学意义(P>0.05);治疗后,两组各项炎症因子水平均明显低于治疗前,且与对照组相比,治疗组超敏C反应蛋白(hs-CRP)、白细胞介素-6(IL-6)、肿瘤坏死因子-α(TNF-α)均明显更低,差异有统计学意义(P<0.05).结论:对老年慢性心力衰竭患者实施益气养阴助阳法联合艾灸神阙穴方案的效果较好,可改善症状积分、心功能相关指标,降低炎症因子水平,且安全性好.
Objective:To analyze the clinical effect of invigorating Qi and nourishing Yin and assisting Yang combined with moxibustion Shenque point on elderly patients with chronic heart failure.Method:A total of 106 elderly patients with chronic heart failure admitted to Baoding No.1 Hospital of Traditional Chinese Medicine from April 2022 to June 2023 were selected and divided into two groups according to random number table method.The 53 patients in the control group received conventional western medicine treatment,and the 53 patients in the treatment group received invigorating Qi and nourishing Yin and assisting Yang treatment.The efficacy and safety,symptom scores,inflammatory factors and cardiac function indexes before and after treatment were compared between the two groups.Result:(1)The total effective rate of treatment group was higher than that of the control group,the difference was statistically significant(P<0.05).There was no difference in the incidence of adverse reactions between groups(P>0.05).(2)Before treatment,there were no significant differences in scores of symptoms between groups(P>0.05).After treatment,the scores of symptoms in both groups were lower than those before treatment,and compared with the control group,the scores of symptoms such as palpitation,chest tightness and chest pain,shortness of breath,lower limb edema in the treatment group were significantly lower,the differences were statistically significant(P<0.05).(3)Before treatment,there were no significant differences in cardiac function related indexes between groups(P>0.05).After treatment,all the indicators related to cardiac function in the two groups were significantly better than those before treatment,and compared with the control group,the left ventricular ejection fraction(LVEF)in the treatment group was significantly higher,the 6 minutes walking distance was significantly longer,and left ventricular end-diastolic diameter(LVEDD),left ventricular end-systolic diameter(LVESD),and amino terminal brain natriuretic peptide precursor(NT-proBNP)were significantly lower,the differences were statistically significant(P<0.05).(4)Before treatment,there were no significant differences in the levels of inflammatory factors between groups(P>0.05).After treatment,the levels of various inflammatory factors in the two groups were significantly lower than those before treatment,and compared with the control group,the hypersensitive C-reactive protein(hs-CRP),interleukin-6(IL-6),tumor necrosis factor-α(TNF-α)in the treatment group were significantly lower,the differences were statistically significant(P<0.05).Conclusion:For elderly patients with chronic heart failure,the effect of invigorating Qi and nourishing Yin and assisting Yang combined with moxibustion Shenque point has better effect,which can improve the symptom score,cardiac function related indicators,reduce the level of inflammatory factors,and has good safety.
辛亚然;石影;高志华;许建;王革;高晶晶;范新发
保定市第一中医院 河北 保定 071000
益气养阴助阳法艾灸神阙穴老年慢性心力衰竭
Invigorating Qi and nourishing Yin and assisting YangMoxibustionShenque acupointElderlyChronic heart failure
《中外医学研究》 2024 (023)
10-14 / 5
2022年保定市科技计划项目(2241ZF071);河北省第五批中医临床优秀人才研修项目(冀中医药函[2022]76号)
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