摘要
Abstract
Objective:To observe the clinical effect of Sanhe Decoction combined with Hydrotalcite Tablets in the treatment of cold congealing Qi stagnation syndrome type stomachache.Method:From December 2022 to December 2023,a total of 110 patients with cold congealing Qi stagnation syndrome type stomachache were selected from Xiamen Hospital of Traditional Chinese Medicine.They were divided into the western medicine group and the combined group,55 cases in each group.The western medicine group was given Hydrotalcite Tablets,and the combined group was given Sanhe Decoction based on the western medicine group.The clinical efficacy,traditional Chinese medicine syndrome points,inflammatory factors before and after treatment,pain degree at different time points and drug adverse reactions were compared between the two groups.Result:The total effective rate of combination group(98.18%)was higher than that of western medicine group(83.64%),and the difference was statistically significant(P<0.05).After treatment,scores of epigastric pain,acid reflux,loss of appetite,epigastric fullness and eructation were decreased in both groups,and scores of epigastric pain,acid reflux,loss of appetite,epigastric fullness and eructation in the combined group were lower than those in the western medicine group,the differences were statistically significant(P<0.05).After 1 week,2 weeks and 4 weeks of treatment,the pain numerical rating scale(NRS)scores of the two groups decreased,and the NRS scores of the combination group were lower than that of the western medicine group,the difference was statistically significant(P<0.05).After treatment,the levels of interleukin-6(IL-6),tumor necrosis factor-α(TNF-α)and procalcitonin(PCT)in the two groups were decreased,and the levels of IL-6,TNF-α and PCT in combination group were lower than those in the western medicine group,the differences were statistically significant(P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion:The treatment effect of Sanhe Decoction combined with Hydrotalcite Tablets on patients with cold coagulation and Qi stagnation type stomach pain is significant,it can significantly reduce the scores of traditional Chinese medicine symptoms,the level of serum inflammatory factors and the degree of pain in patients,and the safety is good.关键词
三合汤/铝碳酸镁片/胃痛/炎症因子Key words
Sanhe Decoction/Hydrotalcite Tablets/Gastralgia/Inflammatory factors
