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Leucine regulates lipid metabolism in adipose tissue through adipokine-mTOR-SIRT1 signaling pathway and bile acid—microbe axis in a finishing pig model

Yunju Yin Saiming Gong Mengmeng Han Jingzun Wang Hanjing Shi Xianji Jiang Liu Guo Yehui Duan Qiuping Guo Qinghua Chen Fengna Li

Animal NutritionIssue(1)：P.158-173,16.

Animal NutritionIssue(1)：P.158-173,16.DOI:10.1016/j.aninu.2023.10.005

Leucine regulates lipid metabolism in adipose tissue through adipokine-mTOR-SIRT1 signaling pathway and bile acid—microbe axis in a finishing pig model

Yunju Yin ¹Saiming Gong ¹Mengmeng Han ²Jingzun Wang ³Hanjing Shi ⁴Xianji Jiang ¹Liu Guo ²Yehui Duan ⁵Qiuping Guo ⁵Qinghua Chen ⁶Fengna Li²

作者信息

1. Key Laboratory of Agro-ecological Processes in Subtropical Region,Institute of Subtropical Agriculture,Chinese Academy of Sciences,Hunan Provincial Key Laboratory of Animal Nutritional Physiology and Metabolic Process,Hunan Provincial Engineering Research Center for Healthy Livestock and Poultry Production,Changsha 410125,China College of Animal Science and Technology,Hunan Agricultural University,Changsha 410128,China
2. Key Laboratory of Agro-ecological Processes in Subtropical Region,Institute of Subtropical Agriculture,Chinese Academy of Sciences,Hunan Provincial Key Laboratory of Animal Nutritional Physiology and Metabolic Process,Hunan Provincial Engineering Research Center for Healthy Livestock and Poultry Production,Changsha 410125,China College of Modern Agricultural Sciences,University of Chinese Academy of Sciences,Beijing 100049,China
3. College of Life Science and Engineering,Northwest Minzu University,Lanzhou 730124,China
4. Key Laboratory of Agro-ecological Processes in Subtropical Region,Institute of Subtropical Agriculture,Chinese Academy of Sciences,Hunan Provincial Key Laboratory of Animal Nutritional Physiology and Metabolic Process,Hunan Provincial Engineering Research Center for Healthy Livestock and Poultry Production,Changsha 410125,China College of Life Sciences,Hunan Normal University,Changsha 410128,China
5. Key Laboratory of Agro-ecological Processes in Subtropical Region,Institute of Subtropical Agriculture,Chinese Academy of Sciences,Hunan Provincial Key Laboratory of Animal Nutritional Physiology and Metabolic Process,Hunan Provincial Engineering Research Center for Healthy Livestock and Poultry Production,Changsha 410125,China
6. College of Animal Science and Technology,Hunan Agricultural University,Changsha 410128,China
折叠

摘要

关键词

Leu/Lipid metabolism/Gut microbiota/Bile acid

分类

农业科技

引用本文复制引用

Yunju Yin,Saiming Gong,Mengmeng Han,Jingzun Wang,Hanjing Shi,Xianji Jiang,Liu Guo,Yehui Duan,Qiuping Guo,Qinghua Chen,Fengna Li..Leucine regulates lipid metabolism in adipose tissue through adipokine-mTOR-SIRT1 signaling pathway and bile acid—microbe axis in a finishing pig model[J].Animal Nutrition,2024,(1):P.158-173,16.

基金项目

supported by National Natural Science Foundation of China(31972582,U22A20516) （31972582,U22A20516）

Science and Technology Innovation Program of Hunan Province(2021RC4039) （2021RC4039）

Key R&D Program of Hunan Province(2022NK2026) （2022NK2026）

the Youth Innovation Promotion Association CAS(Y202079) （Y202079）

Animal Nutrition

ISSN：2405-6545

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