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Inhibition of the cGAS–STING pathway:contributing to the treatment of cerebral ischemia-reperfusion injury

Hang Yang Yulei Xia Yue Ma Mingtong Gao Shuai Hou Shanshan Xu Yanqiang Wang

Neural Regeneration Research2025，Vol.20Issue(7)：P.1900-1918,19.

Neural Regeneration Research2025，Vol.20Issue(7)：P.1900-1918,19.DOI:10.4103/NRR.NRR-D-24-00015

Inhibition of the cGAS–STING pathway:contributing to the treatment of cerebral ischemia-reperfusion injury

Hang Yang ¹Yulei Xia ¹Yue Ma ¹Mingtong Gao ²Shuai Hou ¹Shanshan Xu ²Yanqiang Wang³

作者信息

1. School of Clinical Medicine,Shandong Second Medical University,Weifang,Shandong Province,China
2. Department of Emergency,The Affiliated Hospital of Weifang Medical University,Weifang,Shandong Province,China
3. Department of Neurology Ⅱ,The Affiliated Hospital of Weifang Medical University,Weifang,Shandong Province,China
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摘要

关键词

calcium homeostasis/cellular autophagy/cerebral ischemia-reperfusion injury/cGAS–STING pathway/ferroptosis/gut–brain–microbiota axis/inflammatory/light chain 3/microglial cells/Syntaxin-17 protein

分类

医药卫生

引用本文复制引用

Hang Yang,Yulei Xia,Yue Ma,Mingtong Gao,Shuai Hou,Shanshan Xu,Yanqiang Wang..Inhibition of the cGAS–STING pathway:contributing to the treatment of cerebral ischemia-reperfusion injury[J].Neural Regeneration Research,2025,20(7):P.1900-1918,19.

基金项目

supported by Yuan Du Scholars,Clinical Research Center of Affiliated Hospital of Shandong Second Medical University,No.2022WYFYLCYJ02 （）

Weifang Key Laboratory,Weifang Science and Technology Development Plan Project Medical Category,No.2022YX093. （）

Neural Regeneration Research

ISSN：1673-5374

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