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首页|期刊导航|Digital Chinese Medicine|Antidepressant effects of Yuanzhi (Polygalae Radix) extract on chronic unpredictable mild stress-induced depression in rats: modulation of the NLRP3 inflammasome and NF-κB pathway

Antidepressant effects of Yuanzhi (Polygalae Radix) extract on chronic unpredictable mild stress-induced depression in rats: modulation of the NLRP3 inflammasome and NF-κB pathway

CHEN Yuzhen ZHAO Yongzhi ZHANG Yiwen CHEN Fang Iqbal Choudhary Muhammad LIU Xinmin JIANG Ning

Digital Chinese Medicine2024,Vol.7Issue(2):P.184-194,11.
Digital Chinese Medicine2024,Vol.7Issue(2):P.184-194,11.DOI:10.1016/j.dcmed.2024.09.009

Antidepressant effects of Yuanzhi (Polygalae Radix) extract on chronic unpredictable mild stress-induced depression in rats: modulation of the NLRP3 inflammasome and NF-κB pathway

CHEN Yuzhen 1ZHAO Yongzhi 2ZHANG Yiwen 3CHEN Fang 1Iqbal Choudhary Muhammad 4LIU Xinmin 5JIANG Ning3

作者信息

  • 1. Institute of Medicinal Plant Development,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100193,China Hunan Engineering and Technology Research Center of Medicinal and Edible Homologous Functional Food,Hunan University of Chinese Medicine,Changsha,Hunan 410208,China
  • 2. Hunan Engineering and Technology Research Center of Medicinal and Edible Homologous Functional Food,Hunan University of Chinese Medicine,Changsha,Hunan 410208,China Pharmay School of Shihezi University/Key Laboratory of Xinjiang Phytomedicine Resource and Utilization,Ministry of Education,Shihezi,Xinjiang 832003,China
  • 3. Institute of Medicinal Plant Development,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100193,China
  • 4. International Center for Chemical and Biological Sciences,University of Karachi,Karachi,Sandh 75270,Pakistan
  • 5. Institute of Drug Discovery Technology,Ningbo University,Ningbo,Zhejiang 315211,China
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摘要

关键词

Depression/Yuanzhi(Polygalae Radix)/Chronic unpredictable mild stress(CUMS)/Proinflammatory cytokine/Neuroinflammatory

分类

医药卫生

引用本文复制引用

CHEN Yuzhen,ZHAO Yongzhi,ZHANG Yiwen,CHEN Fang,Iqbal Choudhary Muhammad,LIU Xinmin,JIANG Ning..Antidepressant effects of Yuanzhi (Polygalae Radix) extract on chronic unpredictable mild stress-induced depression in rats: modulation of the NLRP3 inflammasome and NF-κB pathway[J].Digital Chinese Medicine,2024,7(2):P.184-194,11.

基金项目

International Cooperative Project of Traditional Chinese Medicine(GZYYG2020023) (GZYYG2020023)

CAMS Innovation Fund for Medical Sciences(CIFMS)Grant(2021-I2M-1-034) (CIFMS)

Key Research Project of Hunan Province(222SK2018). (222SK2018)

Digital Chinese Medicine

2096-479X

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